Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5358414 | 0.81 | TRPA1 (0.44) | ACHETSHRGABRA1GABRB2PDK2 | |
| SCHEMBL3277341 | 0.80 | ACHE (0.43) | ACHETSHRGABRA1GABRB2HSD11B1 | |
| SCHEMBL16105712 | 0.80 | ACHE (0.43) | ACHETSHRGABRA1GABRB2HSD11B1 | |
| SCHEMBL11623026 | 0.79 | ACHE (0.47) | ACHETSHRGABRA1GABRB2HSD11B1 | |
| SCHEMBL169124 | 0.79 | TSHR (0.47) | ACHETSHRGABRA1GABRB2HSD11B1 | |
| SCHEMBL29656610 | 0.79 | TSHR (0.47) | ACHETSHRGABRA1GABRB2HSD11B1 | |
| SCHEMBL13324333 | 0.78 | ACHE (0.41) | ACHETSHRGABRA1GABRB2HSD11B1 | |
| SCHEMBL5958679 | 0.78 | CD44 (0.46) | ACHETSHRGABRA1GABRB2PDK2 | |
| Ammonia Solution, Strong SCHEMBL1870627 | 0.77 | HSD11B1 (0.45) | ACHETSHRGABRA1GABRB2HSD11B1 | |
| SCHEMBL10034988 | 0.77 | ACHE (0.45) | ACHETSHRGABRA1GABRB2HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104803826-B | A kind of method utilizing hexafluoropropene that aryl boric acid directly aoxidizes seven fluorine isopropylations | 中国科学院上海有机化学研究所 | 2016-08-17 | — | — | CN | disclosed |
| CN-104803826-A | Method for directly oxidizing arylboronic acid into heptafluoroisopropyl by utilizing hexafluoropropylene | SHANGHAI INST ORGANIC CHEM | 2015-07-29 | — | — | CN | disclosed |
| US-7169955-B2 | Perfluoroisopropylbenzene derivative | NIHON NOHYAKU CO., LTD. (JP) | 2007-01-30 | — | — | US | disclosed |
| US-20050113567-A1 | Perfluoroisopropylbenzene derivative | NIHON NOHYAKU CO., LTD. (JP) | 2005-05-26 | — | — | US | disclosed |
| US-20030187233-A1 | PERFLUOROISOPROPYBENZENE DERIVATIVE | NIHON NOHYAKU CO., LTD. (JP) | 2003-10-02 | — | — | US | disclosed |
| EP-1253128-A1 | PERFLUOROISOPROPYLBENZENE DERIVATIVES | Nihon Nohyaku Co., Ltd. (JP) | 2002-10-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187233-A1 | PERFLUOROISOPROPYBENZENE DERIVATIVE | AFF1, CBR1, RER1 | ACHE 3978/4885TSHR 232/4885GABRA1 1819/4885 |
| US-20050113567-A1 | Perfluoroisopropylbenzene derivative | FFAR3, CBR3, HCAR3 | ACHE 3516/4885TSHR 60/4885GABRA1 874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.