SCHEMBL957653

SCHEMBL957653

O=[C]C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
THRB P10828 1/20 0.38
CA2 P00918 2/20 0.35
CA1 P00915 1/20 0.32
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
MMP8 P22894 1/20 0.32
MMP13 P45452 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7779858 1.00 LMNA (0.38) LMNATHRBCA2CA1MMP1
SCHEMBL955673 1.00 LMNA (0.38) LMNATHRBCA2CA1MMP1
SCHEMBL7782669 1.00 LMNA (0.38) LMNATHRBCA2CA1MMP1
SCHEMBL957475 1.00 LMNA (0.38) LMNATHRBCA2CA1MMP1
SCHEMBL6656018 1.00 LMNA (0.38) LMNATHRBCA2CA1MMP1
SCHEMBL953592 1.00 LMNA (0.38) LMNATHRBCA2CA1MMP1
SCHEMBL956942 1.00 LMNA (0.38) LMNATHRBCA2CA1MMP1
SCHEMBL465609 1.00 LMNA (0.38) LMNATHRBCA2CA1MMP1
SCHEMBL536268 1.00 LMNA (0.38) LMNATHRBCA2CA1MMP1
SCHEMBL835510 0.97 LMNA (0.33) LMNATHRBCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7041518-A None JP disclosed
CN-112771087-B Process for producing polytetrafluoroethylene 大金工业株式会社 2023-01-20 CN disclosed
CN-109942553-B Synthesis and conversion method of chiral 3,4, 6-trisubstituted tetrahydro 2H-pyran-2-one compound 大连理工大学 2020-09-29 CN disclosed
EP-2841433-B1 TETRAZOLINONE COMPOUNDS AND ITS USE SUMITOMO CHEMICAL CO (JP) 2017-06-21 EP disclosed
US-9380782-B2 Tetrazolinone compounds and its use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-07-05 US disclosed
EP-2841433-A1 TETRAZOLINONE COMPOUNDS AND ITS USE Sumitomo Chemical Company Limited (JP) 2015-03-04 EP disclosed
US-20150031733-A1 TETRAZOLINONE COMPOUNDS AND ITS USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-01-29 US disclosed
WO-2013162077-A1 TETRAZOLINONE COMPOUNDS AND ITS USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-10-31 WO disclosed
US-20130029928-A1 COMPOSITIONS COMPRISING PERFLUOROOCTANOIC ACID CXR BIOSCIENCES LIMITED (GB) 2013-01-31 US disclosed
WO-2012133928-A1 TRIMERIZATION CATALYST AND METHOD FOR PRODUCING 1-HEXENE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-04 WO disclosed
US-20050245701-A1 Process for producing modified particle; carrier; catalyst component for addition polymerization; process for producing catalyst for addition polymerization; and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2005-11-03 US disclosed
US-20050222351-A1 Process for producing compound, catalyst component for addition polymerization, process for producing catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2005-10-06 US disclosed
US-20050192178-A1 Modified particle, catalyst component for addition polymerization, catalyst for addition polymerization and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-09-01 US disclosed
US-20050148459-A1 Process for producing modified particle, carrier or catalyst component for addition polymerization, pre-polymerized catalyst component therefor, catalyst therefor, and addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2005-07-07 US disclosed
JP-2001247497-A PERFLUORODECALYL GROUP-CONTAINING PEROXIDE, PERFLUORODECALYL GROUP-CONTAINING COMPOUND AND THEIR PRODUCTION METHOD ISHIHARA CHEM CO LTD 2001-09-11 JP disclosed
US-6106999-A SENSITIVITY TO GENERAL-PURPOSE VISIBLE LIGHT LASER, SO THAT HIGH-SPEED SCANNING EXPOSURE IS POSSIBLE BY LASER, AND EXTREMELY FINE HIGH RESOLUTION CAN BE OBTAINED; CAN BE USED FOR COATING OR PRINTING UNDER SAFELIGHT IRRADIATING CONDITIONS MITSUI CHEMICALS (JP) 2000-08-22 US disclosed
US-5728641-A Catalyst component for the polymerization of olefins NIPPON OIL COMPANY, LIMITED (JP) 1998-03-17 US disclosed
US-5556821-A Catalyst component for the polymerization of olefins NIPPON OIL COMPANY, LIMITED (JP) 1996-09-17 US disclosed
JP-H0741518-A FLUORINATED POLYMER AND MEDICAL SUPPLY MADE USING THE SAME KURARAY CO LTD 1995-02-10 JP disclosed
EP-0587440-A2 Catalyst component for the polymerisation of olefins and process for preparing olefin polymers using same NIPPON OIL COMPANY, LIMITED (JP) 1994-03-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150031733-A1 TETRAZOLINONE COMPOUNDS AND ITS USE CBR3, CYP51A1, CYP8B1 LMNA 3920/4885THRB 706/4885CA2 1497/4885
US-20130029928-A1 COMPOSITIONS COMPRISING PERFLUOROOCTANOIC ACID SLC10A1, SLC26A3, SLC26A4 LMNA 2410/4885THRB 1904/4885CA2 406/4885
US-20050222351-A1 Process for producing compound, catalyst component for addition polymerization, process for producing catalyst for addition polymerization, and process for producing addition polymer CCNT1, C5, C9 LMNA 2592/4885THRB 3963/4885CA2 2826/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.