Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8482994 | 0.76 | DYRK1A (0.58) | DYRK1AHTR6KMT2AKDM4EALDH1A1 | |
| SCHEMBL14519052 | 0.75 | PTGS2 (0.64) | DYRK1AHTR6KMT2AKDM4EALDH1A1 | |
| SCHEMBL5356842 | 0.73 | KDM4E (0.49) | DYRK1AHTR6KMT2AKDM4EALDH1A1 | |
| SCHEMBL5358145 | 0.73 | SIRT2 (0.52) | HTR6KMT2AALDH1A1NPSR1TSHR | |
| SCHEMBL5355112 | 0.72 | HTR6 (0.60) | HTR6KDM4EL3MBTL1 | |
| SCHEMBL28576106 | 0.68 | KMT2A (0.57) | DYRK1AHTR6KMT2AKDM4EALDH1A1 | |
| SCHEMBL4305410 | 0.68 | KMT2A (0.70) | DYRK1AKMT2AKDM4EALDH1A1THRB | |
| SCHEMBL14301382 | 0.68 | KMT2A (0.61) | DYRK1AHTR6KMT2AKDM4EALDH1A1 | |
| SCHEMBL28492381 | 0.68 | PTGS2 (0.55) | KMT2AKDM4EALDH1A1THRBPTGS2 | |
| SCHEMBL20563710 | 0.68 | PTGS2 (0.47) | DYRK1AHTR6KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176230-B2 | Synthesis of indole analogs of 1-benzyl-3-(5′-hydroxymethyl-2′-furyl) indazole (YC-1) as anti-platelet agents | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2007-02-13 | — | — | US | disclosed |
| US-20060106041-A1 | Synthesis of indole analogs of 1-benzyl-3-(5'-hydroxymethy 1-2' -furyl) indazole (YC-1) as anti-platelet agents | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2006-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060106041-A1 | Synthesis of indole analogs of 1-benzyl-3-(5'-hydroxymethy 1-2' -furyl) indazole (YC-1) as anti-platelet agents | PFKP, HMOX1, TPH1 | DYRK1A 243/4885HTR6 85/4885KMT2A 2910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.