Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | KDR | P35968 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.44 |
| ▸ | PLEC | Q15149 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4914715 | 0.85 | ALDH1A1 (0.48) | HDAC6TDP1KDRMEN1KMT2A | |
| SCHEMBL5363055 | 0.84 | EGLN1 (0.51) | HDAC6TDP1KDRMEN1KMT2A | |
| SCHEMBL5360442 | 0.73 | MAPT (0.61) | TDP1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL5365460 | 0.72 | TSHR (0.50) | TDP1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL10505456 | 0.72 | ALDH1A1 (0.60) | HDAC6TDP1KDRMEN1KMT2A | |
| SCHEMBL5359196 | 0.72 | EGLN1 (0.50) | HDAC6KDRMEN1KMT2AMAPT | |
| SCHEMBL379216 | 0.71 | GLO1 (0.59) | HDAC6TDP1KDRMEN1KMT2A | |
| SCHEMBL19631407 | 0.70 | HDAC6 (0.75) | HDAC6TDP1KDRMEN1KMT2A | |
| SCHEMBL29851236 | 0.69 | KDR (0.71) | HDAC6TDP1KDRMEN1KMT2A | |
| SCHEMBL1695444 | 0.69 | KDR (0.71) | HDAC6TDP1KDRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007138110-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | claimed |