Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.59 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.49 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5363575 | 1.00 | HCAR2 (0.59) | HCAR2PTGER1PTGER4PTGER3PTGER2 | |
| Hydrochloric Acid SCHEMBL5352171 | 0.98 | HCAR2 (0.58) | HCAR2PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL3463121 | 0.85 | HCAR2 (0.47) | HCAR2ALDH1A1LMNACYP2D6CYP2C19 | |
| SCHEMBL26228656 | 0.85 | ALDH1A1 (0.53) | HCAR2ALDH1A1LMNAMAPK1L3MBTL1 | |
| SCHEMBL5766428 | 0.85 | ALDH1A1 (0.53) | HCAR2ALDH1A1LMNAMAPK1L3MBTL1 | |
| SCHEMBL5352165 | 0.85 | ALDH1A1 (0.53) | HCAR2PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL10348825 | 0.83 | HCAR2 (0.69) | HCAR2ALDH1A1LMNAMAPK1L3MBTL1 | |
| SCHEMBL10348824 | 0.83 | HCAR2 (0.69) | HCAR2ALDH1A1LMNAMAPK1L3MBTL1 | |
| SCHEMBL27488705 | 0.83 | GPR52 (0.53) | HCAR2ALDH1A1KDM4EPKMLMNA | |
| SCHEMBL11009967 | 0.82 | HCAR2 (0.49) | HCAR2ALDH1A1LMNACA12AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7230119-B2 | Process for the preparation of substituted pyrrolidine derivatives and intermediates | BIOCRYST PHARMACEUTICALS, INC. (US) | 2007-06-12 | — | — | US | disclosed |
| US-20060128789-A1 | Process for the preparation of substituted pyrrolidine derivatives and intermediates | BIOCRYST PHARMACEUTICALS, INC. (US) | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128789-A1 | Process for the preparation of substituted pyrrolidine derivatives and intermediates | PNISR, PNMT, GRHPR | HCAR2 955/4885PTGER1 2152/4885PTGER4 691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.