Thiodiglycol

Thiodiglycol

SCHEMBL6850647

NC(=O)C(=O)NCC(O)O.OCCSCCO

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.37
TGFBR1 P36897 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL536399 0.84 TGFBR1 (0.37) TGFBR1
SCHEMBL561651 0.70 KMT2A (0.34)
SCHEMBL2330624 0.67 KDM4E (0.38) TGFBR1
SCHEMBL15808661 0.67 KDM4E (0.38) TGFBR1
SCHEMBL28969443 0.67 KDM4E (0.33) TGFBR1
SCHEMBL30662613 0.66 TSHR (0.48) TDP1
SCHEMBL538750 0.65
SCHEMBL4727074 0.65
SCHEMBL5001767 0.65 CYP2D6 (0.54) TGFBR1
SCHEMBL13857911 0.65 TGFBR1 (0.35) TGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6784235-B2 A POLYOLEFIN FILMS HAVING INCORPORATED THEREIN A COMPOUND OF THE FORMULA CH3CH2(CH2CH2)ACH2CH2(OCH2CH2)BOH, WHERE A IS 9 TO 25 AND B IS 1 TO 10, EXHIBIT SUPERIOR FOG RESISTANCE; USEFUL AS PACKAGING FILM FOR FOOD AND AS GREENHOUSE FILM CIBA SPECIALTY CHEMICALS CORPORATION 2004-08-31 US disclosed
US-20030120077-A1 Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES PETER (US) 2003-06-26 US disclosed
US-20010047046-A1 Polyolefin film compositions with permanent antifog properties TECHMER PM, LLC 2001-11-29 US disclosed
EP-0845458-B1 1,2-Bis-adducts of stable nitroxides with substituted enthylenes and stabilized compositions CIBA SC HOLDING AG (CH) 2001-11-07 EP disclosed
US-5668198-A Polymer stabilizers containing both hindered amine and hydroxylamine moieties CIBA-GEIGY CORPORATION (US) 1997-09-16 US disclosed
US-5668199-A Polymer stabilizers containing both hindered amine and hydroxylamine moieties CIBA-GEIGY CORPORATION (US) 1997-09-16 US disclosed
EP-0573393-B1 Perfluoroalkyl substituted hydroxyphenylalkanoic ester antioxidants CIBA GEIGY AG (CH) 1995-12-06 EP disclosed
EP-0572554-A1 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS Ciba SC Holding AG (CH) 1993-12-08 EP disclosed
WO-1992014717-A1 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS CIBA-GEIGY AG (CH) 1992-09-03 WO disclosed
EP-0252007-A2 2-Propanol derivatives as corrosion inhibitors CIBA-GEIGY AG (CH) 1988-01-07 EP disclosed
EP-0029803-B1 ORGANIC POLYMERIC MATERIALS STABILIZED WITH CALCIUM STEAROYL LACTATE K.K. Musashino Kagaku Kenkyusho (JP) 1985-06-19 EP disclosed
EP-0029803-A2 Organic polymeric materials stabilized with calcium stearoyl lactate K.K. Musashino Kagaku Kenkyusho (JP) 1981-06-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030120077-A1 Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith OGG1, POLH, OGFOD1 TDP1 688/4885TGFBR1 4308/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.