SCHEMBL536470

SCHEMBL536470

CC(COC(=O)CCCCC(=O)O)COC(=O)CCCCC(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.52
TSHR P16473 4/20 0.48
LMNA P02545 4/20 0.46
ALDH1A1 P00352 3/20 0.46
TDP1 Q9NUW8 2/20 0.46
CYP3A4 P08684 1/20 0.46
ATM Q13315 1/20 0.46
PAM P19021 2/20 0.46
KDM4E B2RXH2 1/20 0.44
DUSP3 P51452 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
NFKB1 P19838 1/20 0.44
PMP22 Q01453 1/20 0.44
AKR1B1 P15121 1/20 0.43
PRKCA P17252 1/20 0.42
PRKCE Q02156 1/20 0.42
PRKCQ Q04759 1/20 0.42
PRKCD Q05655 1/20 0.42
GPR84 Q9NQS5 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14674390 0.90 MAPT (0.51) MAPTTSHRLMNAALDH1A1TDP1
SCHEMBL537245 0.90 LMNA (0.49) MAPTTSHRLMNAALDH1A1TDP1
SCHEMBL409033 0.88 MAPT (0.52) MAPTTSHRLMNAALDH1A1TDP1
SCHEMBL27865301 0.87 EGLN1 (0.45) MAPTTSHRLMNAALDH1A1TDP1
SCHEMBL28029409 0.87 TSHR (0.51) MAPTTSHRLMNAALDH1A1TDP1
SCHEMBL14674409 0.86 TSHR (0.48) MAPTTSHRLMNAALDH1A1TDP1
SCHEMBL27216258 0.86 MAPT (0.55) MAPTTSHRLMNAALDH1A1TDP1
SCHEMBL5487490 0.86 MAPT (0.55) MAPTTSHRLMNAALDH1A1TDP1
SCHEMBL605904 0.86 MAPT (0.70) MAPTTSHRLMNAALDH1A1TDP1
SCHEMBL29054062 0.86 TSHR (0.58) MAPTTSHRLMNAALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12029798-B2 Pre-targeting strategies for molecular imaging and/or radioimmunotherapy University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2024-07-09 US disclosed
US-11931423-B2 Glucose oxidase-nanoparticle bioconjugates for cancer treatment University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2024-03-19 US disclosed
US-11857648-B2 Dimerization strategies and compounds for molecular imaging and/or radioimmunotherapy University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2024-01-02 US disclosed
WO-2023052127-A1 PVC MIXTURE LEONI KABEL GMBH (DE) 2023-04-06 WO disclosed
EP-2997076-B1 SUPRAMOLECULAR BIODEGRADABLE POLYMER SUPRAPOLIX BV (NL) 2022-03-16 EP disclosed
US-20200085966-A1 GLUCOSE OXIDASE-NANOPARTICLE BIOCONJUGATES FOR CANCER TREATMENT AND USES THEREOF UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2020-03-19 US disclosed
US-20190134240-A1 DIMERIZATION STRATEGIES AND COMPOUNDS FOR MOLECULAR IMAGING AND/OR RADIOIMMUNOTHERAPY UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2019-05-09 US disclosed
US-20190134239-A1 PRE-TARGETING STRATEGIES FOR MOLECULAR IMAGING AND/OR RADIOIMMUNOTHERAPY UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2019-05-09 US disclosed
EP-2705879-B1 COMBINATION OF OILS FOR ANTIPERSPIRANT COMPOSITIONS WITH IMPROVED WHITE MARK PROTECTION HENKEL AG & CO KGAA (DE) 2017-06-07 EP disclosed
EP-2480192-B1 NON-AEROSOL WATER-FREE ANTIPERSPIRANT IN WHICH ACTIVE SUBSTANCES ARE MORE READILY RELEASED HENKEL AG & CO KGAA (DE) 2016-01-13 EP disclosed
EP-2480193-B1 NON-AEROSOL WATER-FREE ANTIPERSPIRANT IN WHICH ACTIVE SUBSTANCES ARE MORE READILY RELEASED HENKEL AG & CO KGAA (DE) 2015-08-19 EP disclosed
EP-2705879-A1 COMBINATION OF OILS FOR ANTIPERSPIRANT COMPOSITIONS WITH IMPROVED WHITE MARK PROTECTION Henkel AG&Co. KGAA (DE) 2014-03-12 EP disclosed
EP-2413890-A2 ANTIPERSPIRANT SPRAYS WITH ESTER OILS Henkel AG & Co. KGaA (DE) 2012-02-08 EP disclosed
WO-2010112459-A2 ANTIPERSPIRANT SPRAYS WITH ESTER OILS HENKEL AG & CO. KGAA (DE) 2010-10-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200085966-A1 GLUCOSE OXIDASE-NANOPARTICLE BIOCONJUGATES FOR CANCER TREATMENT AND USES THEREOF G6PD, PPOX, DUOX1 MAPT 1559/4885TSHR 1477/4885LMNA 4207/4885
US-20190134239-A1 PRE-TARGETING STRATEGIES FOR MOLECULAR IMAGING AND/OR RADIOIMMUNOTHERAPY CD47, PAICS, MKI67 MAPT 1630/4885TSHR 1676/4885LMNA 564/4885
US-20190134240-A1 DIMERIZATION STRATEGIES AND COMPOUNDS FOR MOLECULAR IMAGING AND/OR RADIOIMMUNOTHERAPY PAICS, CD47, BID MAPT 2318/4885TSHR 302/4885LMNA 3438/4885
US-11931423-B2 Glucose oxidase-nanoparticle bioconjugates for cancer treatment G6PD, PPOX, DUOX1 MAPT 1453/4885TSHR 1513/4885LMNA 4224/4885
US-11857648-B2 Dimerization strategies and compounds for molecular imaging and/or radioimmunotherapy PAICS, CD47, BID MAPT 2318/4885TSHR 302/4885LMNA 3438/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.