Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6316984 | 0.89 | CHUK (0.32) | CHUKLMNAALDH1A1CYP2C19 | |
| SCHEMBL14049093 | 0.86 | TLR8 (0.33) | CHUKLMNAALDH1A1CYP2C19 | |
| SCHEMBL13267148 | 0.86 | CHUK (0.30) | CHUKLMNA | |
| SCHEMBL2054828 | 0.81 | — | — | |
| Water SCHEMBL8865234 | 0.76 | ALDH1A1 (0.33) | ALDH1A1CYP2C19 | |
| SCHEMBL28483907 | 0.76 | — | — | |
| SCHEMBL8469612 | 0.76 | — | — | |
| SCHEMBL1703076 | 0.74 | ALDH1A1 (0.33) | ALDH1A1CYP2C19 | |
| SCHEMBL15868904 | 0.74 | CA1 (0.38) | CYP2C19 | |
| SCHEMBL5175689 | 0.74 | TLR8 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 284 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119350339-A | Preparation method and application of abacavir impurity | 安徽贝克制药股份有限公司 | 2025-01-24 | — | — | CN | claimed |
| CN-117050024-B | Synthesis method of 2-amino-4, 6-dichloro-5-formamidopyrimidine | 苏州开元民生科技股份有限公司 | 2024-01-05 | — | — | CN | claimed |
| CN-117050024-A | Synthesis method of 2-amino-4, 6-dichloro-5-formamidopyrimidine | 苏州开元民生科技股份有限公司 | 2023-11-14 | — | — | CN | claimed |
| CN-115536595-B | Synthesis method of 2-amino-4, 6-dichloro-5-formamido pyrimidine | 苏州开元民生科技股份有限公司 | 2023-03-10 | — | — | CN | claimed |
| CN-115536595-A | Synthesis method of 2-amino-4, 6-dichloro-5-formamido pyrimidine | 苏州开元民生科技股份有限公司 | 2022-12-30 | — | — | CN | claimed |
| CN-112062726-B | Preparation method of 2-amino-4, 6-dichloro-5-formamido pyrimidine | 苏州开元民生科技股份有限公司 | 2021-02-09 | — | — | CN | claimed |
| CN-112062726-A | Preparation method of 2-amino-4, 6-dichloro-5-formamido pyrimidine | 苏州开元民生科技股份有限公司 | 2020-12-11 | — | — | CN | claimed |
| CN-105646372-B | preparation method of 2-amino-4, 6-dichloro-5-formamido pyrimidine | 北京英力精化技术发展有限公司 | 2019-12-10 | — | — | CN | claimed |
| CN-105646372-A | Preparation method of 2-amino-4,6-dichloro-5-formamine pyrimidine | 北京英力精化技术发展有限公司 | 2016-06-08 | — | — | CN | claimed |
| EP-2170840-A1 | AN IMPROVED PROCESS FOR PREPARING PURINE DERIVATIVE | Aurobindo Pharma Ltd (IN) | 2010-04-07 | — | — | EP | claimed |
| WO-2005068438-A1 | METHOD FOR PRODUCING 2-AMINO-4,6-DICHLORO-5-FORMAMIDOPYRIMIDINE | DEGUSSA AG (DE) | 2005-07-28 | — | — | WO | claimed |
| EP-0878548-B1 | Multistep process for the preparation of (1S,4R)- and/or (1R,4S)-4-(2-Amino-6-Chlor-9-H-purin-9-yl)-2-cyclopentene-1-methanol | LONZA AG (CH) | 2004-09-01 | — | — | EP | claimed |
| US-20040142436-A1 | Process for the preparation of aminoalcohol derivatives and their further conversion to (1R,4S)-4-(2-amino-6-chloro-5-formamido-4-pyrimidinyl)-amino)-2-cyclopentenyl-1-methanol | BRIEDEN WALTER (CH) | 2004-07-22 | — | — | US | claimed |
| US-6448402-B2 | REDUCTION OF 2-AZABICYCLO(2.2.1)HEPT-5-EN-3-ONE USING METAL HYRIDE | LONZA AG (CH) | 2002-09-10 | — | — | US | claimed |
| US-20020010360-A1 | Process for the preparation of aminoalcohol derivatives and their further conversion to (1R, 4S)-4-((2-amino-6-chloro-5-formamido-4-pyrimidinyl)-amino)-2-cyclopentenyl-1- methanol | LONZA AG (CH) | 2002-01-24 | — | — | US | claimed |
| US-6156893-A | Process for the preparation of (1S,4R)- or (1R,4S)- 4-(2-amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol | LONZA A.G. (CH) | 2000-12-05 | — | — | US | claimed |
| EP-0684236-B1 | N-(2-Amino-4,6-dichloropyrimidin-5-yl)formamide and process for its production | LONZA AG (CH) | 1998-06-24 | — | — | EP | claimed |
| US-5744601-A | N-(2-amino-4, 6-dichlopyrimidine-5-yl) formanide, and a process for its preparation | LONZA AG (CH) | 1998-04-28 | — | — | US | claimed |
| US-5663340-A | N-(2-amino-4,6-dichloropyrimidine-5-yl)formamide, and a process for its preparation | LONZA AG (CH) | 1997-09-02 | — | — | US | claimed |
| EP-0684236-A2 | N-(2-Amino-4,6-dichloropyrimidin-5-yl)formamide and process for its production | LONZA AG (CH) | 1995-11-29 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020010360-A1 | Process for the preparation of aminoalcohol derivatives and their further conversion to (1R, 4S)-4-((2-amino-6-chloro-5-formamido-4-pyrimidinyl)-amino)-2-cyclopentenyl-1- methanol | AASDHPPT, ALDH7A1, AADAT | CHUK 3075/4885LMNA 2717/4885ALDH1A1 69/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.