SCHEMBL5367352

SCHEMBL5367352

CC(C)(C)c1ccc2c(c1CC(c1c(C(C)(C)C)ccc3c1Cc1ccccc1-3)[Zr](Cl)Cl)Cc1ccccc1-2

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5347003 0.82 PNMT (0.33) PNMT
SCHEMBL7607198 0.82 PNMT (0.35) PNMT
SCHEMBL7605736 0.82 PNMT (0.38) PNMT
SCHEMBL7604906 0.81 PNMT (0.38) PNMT
SCHEMBL7609391 0.80 PGR (0.36) PNMT
SCHEMBL7605739 0.78 PNMT (0.41) PNMT
SCHEMBL5351579 0.78 PNMT (0.36) PNMT
SCHEMBL7607200 0.76 PNMT (0.41) PNMT
Hydrochloric Acid SCHEMBL5347006 0.74 PNMT (0.41) PNMT
Hydrochloric Acid SCHEMBL5353791 0.74 PNMT (0.41) PNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0524624-B1 Use of organometallic flurorenyl compounds. PHILLIPS PETROLEUM CO (US) 2002-05-15 EP claimed
US-5436305-A Preparing polymer catalysts by reaction of alkali metal alkyl and fluorenyl in solvent PHILLIPS PETROLEUM COMPANY (US) 1995-07-25 US claimed
EP-0524624-A2 Organometallic fluorenyl compounds, preparation, and use PHILLIPS PETROLEUM COMPANY (US) 1993-01-27 EP claimed
US-7230128-B2 Organometallic fluorenyl compounds, preparations, and use PHILLIPS POTROLEUM COMPANY (US) 2007-06-12 US disclosed
US-20060122344-A1 Organometallic Fluorenyl Compounds, Preparations, and Use PHILLIPS PETROLEUM COMPANY (US) 2006-06-08 US disclosed
US-6420579-B1 SILYL, GERMANIUM OR TIN RADICALS WITH TITANIUM, ZIRCONIUM, HAFNIUM, VANADIUM, NIOBIUM AND TANTALUM METALS PHILLIPS PETROLEUM COMPANY 2002-07-16 US disclosed
US-6403734-B1 POLYMERIZING ALPHA-OLEFIN BY CONTACTING WITH CATALYST SYSTEM COMPRISING BRIDGED FLUORENYL METALLOCENE CONTAINING METAL OF GROUP 4 OR 5 AND SUITABLE COCATALYST PHILLIPS PETROLEUM COMPANY 2002-06-11 US disclosed
EP-0524624-B1 Use of organometallic flurorenyl compounds. PHILLIPS PETROLEUM CO (US) 2002-05-15 EP disclosed
EP-0666267-B1 Organometallic fluorenyl compounds, preparation, and use PHILLIPS PETROLEUM CO (US) 2001-04-18 EP disclosed
US-6162936-A Organometallic fluorenyl compounds, preparation, and use PHILLIPS PETROLEUM COMPANY (US) 2000-12-19 US disclosed
US-5571880-A CATALYSTS FOR POLYMERIZATION OF OLEFINS ESPECIALLY TO OBTAIN SYNDIOTACTIC POLYMERS PHILLIPS PETROLEUM COMPANY (US) 1996-11-05 US disclosed
EP-0666267-A2 Organometallic fluorenyl compounds, preparation, and use PHILLIPS PETROLEUM COMPANY (US) 1995-08-09 EP disclosed
US-5436305-A Preparing polymer catalysts by reaction of alkali metal alkyl and fluorenyl in solvent PHILLIPS PETROLEUM COMPANY (US) 1995-07-25 US disclosed
EP-0524624-A2 Organometallic fluorenyl compounds, preparation, and use PHILLIPS PETROLEUM COMPANY (US) 1993-01-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060122344-A1 Organometallic Fluorenyl Compounds, Preparations, and Use HMBS, FDPS, SOD1 PNMT 7/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.