Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740346 | 0.95 | L3MBTL1 (0.51) | L3MBTL1KMT2AMEN1POLBCYP2D6 | |
| SCHEMBL9205385 | 0.94 | L3MBTL1 (0.54) | L3MBTL1KMT2AMEN1POLBCYP2D6 | |
| SCHEMBL892946 | 0.91 | HDAC1 (0.51) | KMT2AMEN1POLBCYP2D6CYP2C9 | |
| SCHEMBL27491805 | 0.91 | HDAC1 (0.51) | KMT2AMEN1POLBCYP2D6CYP2C9 | |
| SCHEMBL6198420 | 0.88 | L3MBTL1 (0.47) | L3MBTL1KMT2AMEN1POLBCYP2D6 | |
| SCHEMBL28116468 | 0.85 | CCR8 (0.51) | KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL5361723 | 0.84 | POLB (0.53) | KMT2APOLBCYP2C9CYP2C19ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5555279 | 0.84 | FKBP1A (0.54) | L3MBTL1KMT2AMEN1POLBCYP2D6 | |
| SCHEMBL14345645 | 0.83 | MEN1 (0.59) | L3MBTL1KMT2AMEN1POLBCYP2D6 | |
| Hydrochloric Acid SCHEMBL10813366 | 0.82 | MEN1 (0.58) | L3MBTL1KMT2AMEN1POLBCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007138110-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | claimed |
| CN-109562113-A | Spirocyclo-rongeur for target protein degradation | C4医药公司 | 2019-04-02 | — | — | CN | disclosed |
| WO-2007138110-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | disclosed |