SCHEMBL892946

SCHEMBL892946

O=C(O)C1CCN(Cc2ccccc2)C1=O

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.51
HDAC8 Q9BY41 1/20 0.51
HDAC6 Q9UBN7 1/20 0.51
KMT2A Q03164 2/20 0.50
POLB P06746 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
GAA P10253 1/20 0.47
PKM P14618 1/20 0.47
ALDH1A1 P00352 1/20 0.45
MEN1 O00255 1/20 0.45
FKBP1A P62942 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27491805 1.00 HDAC1 (0.51) HDAC1HDAC8HDAC6KMT2APOLB
SCHEMBL5369178 0.91 L3MBTL1 (0.49) HDAC1HDAC8HDAC6KMT2APOLB
SCHEMBL9740346 0.89 L3MBTL1 (0.51) HDAC1HDAC8HDAC6KMT2APOLB
SCHEMBL9205385 0.88 L3MBTL1 (0.54) HDAC1HDAC8HDAC6KMT2APOLB
SCHEMBL7779965 0.88 HDAC1 (0.49) HDAC1HDAC8HDAC6KMT2APOLB
SCHEMBL13326692 0.88 HDAC1 (0.52) HDAC1HDAC8HDAC6KMT2APOLB
SCHEMBL7829097 0.88 HDAC1 (0.49) HDAC1HDAC8HDAC6KMT2APOLB
SCHEMBL5980733 0.85 HDAC1 (0.47) HDAC1HDAC8HDAC6KMT2APOLB
SCHEMBL5979605 0.85 HDAC1 (0.47) HDAC1HDAC8HDAC6KMT2APOLB
SCHEMBL28116823 0.84 CCR8 (0.53) KMT2APOLBGAAALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260022095-A1 COMPOUNDS USEFUL FOR THE PREPARATION OF VARIOUS AGROCHEMICALS AND MARKERS THEREOF ADAMA AGAN LTD. (IL) 2026-01-22 US disclosed
US-20250197350-A1 COMPOUNDS USEFUL FOR THE PREPARATION OF VARIOUS AGROCHEMICALS AND MARKERS THEREOF ADAMA AGAN LTD. (IL) 2025-06-19 US disclosed
US-20250066297-A1 COMPOUNDS USEFUL FOR THE PREPARATION OF VARIOUS AGROCHEMICALS AND MARKERS THEREOF ADAMA AGAN LTD. (IL) 2025-02-27 US disclosed
EP-4508980-A2 COMPOUNDS USEFUL FOR THE PREPARATION OF VARIOUS AGROCHEMICALS AND MARKERS THEREOF Adama Agan Ltd. (IL) 2025-02-19 EP disclosed
EP-4483714-A2 COMPOUNDS USEFUL FOR THE PREPARATION OF VARIOUS AGROCHEMICALS AND MARKERS THEREOF Adama Agan Ltd. (IL) 2025-01-01 EP disclosed
EP-4447681-A2 COMPOUNDS USEFUL FOR THE PREPARATION OF VARIOUS AGROCHEMICALS AND MARKERS THEREOF Adama Agan Ltd. (IL) 2024-10-23 EP disclosed
CN-118401112-A Compounds for preparing various agrochemicals and markers thereof 安道麦阿甘有限公司 2024-07-26 CN disclosed
EP-4063358-B1 HISTONE METHYLTRANSFERASE INHIBITORS GLOBAL BLOOD THERAPEUTICS INC (US) 2024-05-22 EP disclosed
US-11713299-B2 Histone methyltransferase inhibitors GLOBAL BLOOD THERAPEUTICS, INC. (US) 2023-08-01 US disclosed
WO-2023112033-A2 COMPOUNDS USEFUL FOR THE PREPARATION OF VARIOUS AGROCHEMICALS AND MARKERS THEREOF ADAMA AGAN LTD. (IL) 2023-06-22 WO disclosed
EP-1395585-B1 ANTIBACTERIAL AGENTS WARNER LAMBERT CO (US) 2006-01-04 EP disclosed
US-6864259-B2 Antibacterial agents WARNER-LAMBERT COMPANY (US) 2005-03-08 US disclosed
EP-1401830-A2 QUINAZOLINEDIONES AS ANTIBACTERIAL AGENTS Warner-Lambert Company LLC (US) 2004-03-31 EP disclosed
US-20030114666-A1 Having quinazolindione core structure; non-antibiotic resistance WARNER-LAMBERT COMPANY 2003-06-19 US disclosed
US-20030114458-A1 Antibacterial agents WARNER-LAMBERT COMPANY 2003-06-19 US disclosed
WO-2002102793-A2 QUINAZOLINEDIONES AS ANTIBACTERIAL AGENTS WARNER-LAMBERT COMPANY LLC (US) 2002-12-27 WO disclosed
EP-0341493-B1 Optically active pyridonecarboxylic acid derivatives DAIICHI SEIYAKU CO (JP) 1999-07-14 EP disclosed
CN-1033751-C Optically active pyridonecarboxylic acid derivatives DAIICHI SEIYAKU CO (JP) 1997-01-08 CN disclosed
US-5175157-A Cardiovascular disorders BOEHRINGER INGELHEIM GMBH (DE) 1992-12-29 US disclosed
EP-0341493-A2 Optically active pyridonecarboxylic acid derivatives DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1989-11-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030114666-A1 Having quinazolindione core structure; non-antibiotic resistance ABCC1, RPS6KA1, SIGMAR1 HDAC1 666/4885HDAC8 2036/4885HDAC6 1768/4885
US-20260022095-A1 COMPOUNDS USEFUL FOR THE PREPARATION OF VARIOUS AGROCHEMICALS AND MARKERS THEREOF TET1, FOXK1, TET3 HDAC1 1226/4885HDAC8 3192/4885HDAC6 3441/4885
US-20030114458-A1 Antibacterial agents MRPL21, RPS6, RPS6KA1 HDAC1 679/4885HDAC8 2138/4885HDAC6 1519/4885
US-20250197350-A1 COMPOUNDS USEFUL FOR THE PREPARATION OF VARIOUS AGROCHEMICALS AND MARKERS THEREOF GYS2, PFAS, CD68 HDAC1 1513/4885HDAC8 1746/4885HDAC6 1574/4885
US-20250066297-A1 COMPOUNDS USEFUL FOR THE PREPARATION OF VARIOUS AGROCHEMICALS AND MARKERS THEREOF GYS2, PFAS, CD68 HDAC1 1513/4885HDAC8 1746/4885HDAC6 1574/4885
US-11713299-B2 Histone methyltransferase inhibitors EHMT1, DOT1L, EHMT2 HDAC1 96/4885HDAC8 179/4885HDAC6 471/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.