Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 10/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5335593 | 0.91 | MPO (0.46) | MPODRD2DRD4DRD3HTR6 | |
| SCHEMBL5327792 | 0.90 | HTR6 (0.52) | MPODRD2DRD4DRD3HTR6 | |
| SCHEMBL5333246 | 0.88 | POLB (0.45) | DRD2DRD4DRD3HTR6POLB | |
| SCHEMBL5333140 | 0.88 | HTR6 (0.48) | HTR6POLB | |
| SCHEMBL5335447 | 0.87 | DRD2 (0.50) | MPODRD2DRD4DRD3HTR6 | |
| SCHEMBL5333836 | 0.86 | HTR6 (0.52) | MPOHTR6POLBCYP3A4CYP2D6 | |
| SCHEMBL5331983 | 0.86 | HTR6 (0.52) | MPOHTR6CYP3A4CYP2D6 | |
| SCHEMBL5330544 | 0.82 | HTR6 (0.43) | MPODRD2DRD4DRD3HTR6 | |
| SCHEMBL5328593 | 0.81 | ALDH1A1 (0.46) | HTR6POLB | |
| SCHEMBL5334580 | 0.80 | ALDH1A1 (0.44) | DRD2DRD4DRD3HTR6POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | claimed |
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | disclosed |