Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5366663 | 0.89 | PDE3B (0.36) | PDE3BPDE3AP2RY12PKMKMT2A | |
| SCHEMBL5370650 | 0.87 | ALDH1A1 (0.37) | ALDH1A1PDE3BPDE3AP2RY12SMN1; SMN2 | |
| SCHEMBL5370920 | 0.81 | CYP2C9 (0.36) | ALDH1A1PDE3BPDE3AP2RY12SMN1; SMN2 | |
| SCHEMBL5359154 | 0.81 | PDE10A (0.40) | ALDH1A1POLBKMT2AMAPK1 | |
| SCHEMBL5358428 | 0.81 | BRS3 (0.46) | ALDH1A1PDE3BPDE3AP2RY12SMN1; SMN2 | |
| SCHEMBL5360419 | 0.76 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2PKMPOLBKMT2A | |
| SCHEMBL5366655 | 0.76 | TP53 (0.36) | PDE3BPDE3AP2RY12SMN1; SMN2PKM | |
| SCHEMBL5370454 | 0.76 | DGAT1 (0.37) | ALDH1A1KMT2AMAPK1 | |
| SCHEMBL5369395 | 0.73 | CYP2C9 (0.35) | ALDH1A1PDE3BPDE3AP2RY12SMN1; SMN2 | |
| SCHEMBL5370913 | 0.73 | ENPP2 (0.34) | ALDH1A1PDE3BPDE3AP2RY12SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7294716-B2 | Process for preparing isomerically pure prodrugs of proton pump inhibitors | ALLERGAN, INC. (US) | 2007-11-13 | — | — | US | disclosed |
| US-20050038076-A1 | Process for preparing isomerically pure prodrugs of proton pump inhibitors | ALEVIUM PHARMACEUTICALS, INC. | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038076-A1 | Process for preparing isomerically pure prodrugs of proton pump inhibitors | SI, ATP6AP1, HRH2 | ALDH1A1 1650/4885PDE3B 2168/4885PDE3A 1817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.