Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5362898 | 0.90 | SMYD3 (0.43) | LMNASMYD3MEN1KMT2A | |
| SCHEMBL5366736 | 0.90 | AKT1 (0.42) | SMYD3 | |
| SCHEMBL5367918 | 0.89 | ALDH1A1 (0.41) | SMYD3ITGB3ITGA2BMEN1KMT2A | |
| SCHEMBL5370964 | 0.85 | KMT2A (0.46) | SMYD3ITGB3ITGA2BMEN1KMT2A | |
| SCHEMBL5366087 | 0.82 | HPGD (0.44) | SMYD3L3MBTL1MEN1KMT2A | |
| SCHEMBL5368815 | 0.75 | CA2 (0.41) | CTSLLMNAITGB3ITGA2B | |
| SCHEMBL5362924 | 0.73 | KMT2A (0.41) | SMYD3ITGB3ITGA2BMEN1KMT2A | |
| SCHEMBL5371022 | 0.72 | KMT2A (0.49) | CTSLSMYD3MEN1KMT2A | |
| SCHEMBL5366617 | 0.70 | ALDH1A1 (0.38) | CTSLLMNA | |
| SCHEMBL5364811 | 0.69 | MEN1 (0.42) | SMYD3MEN1KMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7259157-B2 | N-substituted nonaryl-heterocyclo amidyl NMDA/NR2B Antagonists | MERCK & CO., INC. (US) | 2007-08-21 | — | — | US | disclosed |