Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SSTR1 | P30872 | 4/20 | 0.43 |
| ▸ | SSTR4 | P31391 | 4/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | SCD | O00767 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5367918 | 0.85 | ALDH1A1 (0.41) | MAPTRAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL5366736 | 0.84 | AKT1 (0.42) | RAB9ASMYD3NPC1SMN1; SMN2 | |
| SCHEMBL5370713 | 0.82 | CTSL (0.42) | MEN1KMT2ASMYD3L3MBTL1 | |
| SCHEMBL5370964 | 0.81 | KMT2A (0.46) | HPGDMAPTRAB9AMEN1POLB | |
| SCHEMBL5362898 | 0.80 | SMYD3 (0.43) | HPGDMAPTRAB9AALDH1A1MEN1 | |
| SCHEMBL5362924 | 0.76 | KMT2A (0.41) | HPGDALDH1A1MEN1POLBKMT2A | |
| SCHEMBL5371022 | 0.75 | KMT2A (0.49) | MAPTRAB9AMEN1POLBKMT2A | |
| SCHEMBL14906914 | 0.72 | HDAC6 (0.57) | HPGDHDAC6MAPTRAB9AALDH1A1 | |
| SCHEMBL5366188 | 0.71 | DEGS1 (0.44) | HPGDMAPTALDH1A1SMYD3 | |
| SCHEMBL5364811 | 0.70 | MEN1 (0.42) | HPGDRAB9AALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7259157-B2 | N-substituted nonaryl-heterocyclo amidyl NMDA/NR2B Antagonists | MERCK & CO., INC. (US) | 2007-08-21 | — | — | US | disclosed |