SCHEMBL5371472

SCHEMBL5371472

COC(=O)C(CC(C)C)NC(=O)CCc1ccc(O)c(O)c1

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ TAS1R3 Q7RTX0 7/20 0.52
▸ TAS1R1 Q7RTX1 7/20 0.52
▸ LCK P06239 1/20 0.51
▸ APP P05067 1/20 0.48
▸ FOLH1 Q04609 4/20 0.47
▸ IAPP P10997 2/20 0.47
▸ ALDH1A1 P00352 1/20 0.46
▸ GAA P10253 2/20 0.46
▸ PKM P14618 1/20 0.46
▸ GFER P55789 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6139811 0.87 LCK (0.67) LCKAPPIAPPALDH1A1GAA
SCHEMBL5378089 0.87 LCK (0.53) LCKAPPIAPPALDH1A1GAA
SCHEMBL5370762 0.87 FOLH1 (0.54) FOLH1IAPPALDH1A1GAA
SCHEMBL5371494 0.82 LCK (0.58) LCKAPPALDH1A1
SCHEMBL28349735 0.80 GAA (0.60) LCKAPPGAAPKM
SCHEMBL28349736 0.80 GAA (0.60) LCKAPPGAAPKM
SCHEMBL11857999 0.79 LCK (0.54) TAS1R3TAS1R1LCKFOLH1
SCHEMBL5370866 0.77 ALDH1A1 (0.49) TAS1R3TAS1R1ALDH1A1
SCHEMBL5370177 0.77 IAPP (0.53) LCKAPPIAPPALDH1A1GAA
SCHEMBL18273972 0.76 IAPP (0.51) LCKAPPIAPPALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7223793-B2 Phenolic acid derivatives and composition for preventing or treating blood lipid level-related diseases comprising the same BIONUTRIGEN CO., LTD. (KR) 2007-05-29 — — US disclosed
US-20030199566-A1 Phenolic acid derivatives and composition for preventing or treating blood lipid level-related diseases comprising the same BIONUTRIGEN CO., LTD. (KR) 2003-10-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030199566-A1 Phenolic acid derivatives and composition for preventing or treating blood lipid level-related diseases comprising the same NCEH1, HMGCR, DBH TAS1R3 1647/4885TAS1R1 1429/4885LCK 3818/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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