SCHEMBL5378089

SCHEMBL5378089

COC(=O)C(CO)NC(=O)CCc1ccc(O)c(O)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LCK P06239 1/20 0.53
▸ APP P05067 2/20 0.50
▸ IAPP P10997 3/20 0.49
▸ GAA P10253 3/20 0.47
▸ PKM P14618 1/20 0.47
▸ GFER P55789 1/20 0.46
▸ ERCC1 P07992 1/20 0.46
▸ ERCC4 Q92889 1/20 0.46
▸ MAPT P10636 2/20 0.45
▸ HPGD P15428 2/20 0.45
▸ MEN1 O00255 1/20 0.45
▸ POLB P06746 1/20 0.45
▸ HTT P42858 1/20 0.45
▸ KMT2A Q03164 1/20 0.45
▸ SMN1; SMN2 Q16637 1/20 0.45
▸ ALDH1A1 P00352 2/20 0.45
▸ ALOX5 P09917 1/20 0.45
▸ OR51E2 Q9H255 1/20 0.45
▸ KDM4E B2RXH2 1/20 0.44
▸ LMNA P02545 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6139811 0.89 LCK (0.67) LCKAPPIAPPGAAPKM
SCHEMBL5371472 0.87 TAS1R3 (0.52) LCKAPPIAPPGAAPKM
SCHEMBL5371494 0.85 LCK (0.58) LCKAPPERCC1ERCC4POLB
SCHEMBL5370755 0.85 ERCC1 (0.52) LCKAPPIAPPGAAERCC1
SCHEMBL28349736 0.82 GAA (0.60) LCKAPPGAAPKMMAPT
SCHEMBL28349735 0.82 GAA (0.60) LCKAPPGAAPKMMAPT
SCHEMBL7281178 0.82 ALDH1A1 (0.53) ALDH1A1KDM4ELMNAHSD17B10HDAC1
SCHEMBL7281189 0.82 ALDH1A1 (0.53) ALDH1A1KDM4ELMNAHSD17B10HDAC1
SCHEMBL9441281 0.82 ALDH1A1 (0.53) ALDH1A1KDM4ELMNAHSD17B10HDAC1
SCHEMBL18273972 0.78 IAPP (0.51) LCKAPPIAPPGAAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7223793-B2 Phenolic acid derivatives and composition for preventing or treating blood lipid level-related diseases comprising the same BIONUTRIGEN CO., LTD. (KR) 2007-05-29 — — US disclosed
US-20030199566-A1 Phenolic acid derivatives and composition for preventing or treating blood lipid level-related diseases comprising the same BIONUTRIGEN CO., LTD. (KR) 2003-10-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030199566-A1 Phenolic acid derivatives and composition for preventing or treating blood lipid level-related diseases comprising the same NCEH1, HMGCR, DBH LCK 3818/4885APP 3404/4885IAPP 2651/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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