Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | LCK | P06239 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | XDH | P47989 | 2/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28349736 | 1.00 | GAA (0.60) | GAAPKMLCKALOX15ALOX12 | |
| SCHEMBL6139811 | 0.92 | LCK (0.67) | GAAPKMLCKAPP | |
| SCHEMBL5371494 | 0.85 | LCK (0.58) | LCKPOLBAPP | |
| SCHEMBL5378089 | 0.82 | LCK (0.53) | GAAPKMLCKKMT2AALOX5 | |
| SCHEMBL5371472 | 0.80 | TAS1R3 (0.52) | GAAPKMLCKAPP | |
| SCHEMBL8410630 | 0.79 | LDHA (0.57) | LCKKMT2AMEN1SMN1; SMN2LDHA | |
| SCHEMBL18273972 | 0.79 | IAPP (0.51) | GAAPKMLCKALOX15ALOX12 | |
| SCHEMBL6267583 | 0.79 | LCK (0.70) | LCKALOX15ALOX12KMT2AXDH | |
| SCHEMBL10099849 | 0.79 | LCK (0.62) | LCK | |
| SCHEMBL28349368 | 0.78 | CNR2 (0.66) | LCKXDHAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110563602-A | rosmarinic acid derivatives, and preparation method and application thereof | 南宁多灵生物科技有限公司 | 2019-12-13 | — | — | CN | claimed |
| CN-110563602-A | rosmarinic acid derivatives, and preparation method and application thereof | 南宁多灵生物科技有限公司 | 2019-12-13 | — | — | CN | disclosed |