Styrene

Styrene

SCHEMBL17836838

C=C(CC=CC#N)C(=O)O.C=CC=C.C=Cc1ccccc1

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39
PAM P19021 1/20 0.35
MCL1 Q07820 1/20 0.32
MAOB P27338 1/20 0.31
NPC1 O15118 1/20 0.30
MAPT P10636 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
PLIN1 O60240 1/20 0.30
LMNA P02545 1/20 0.30
PLIN5 Q00G26 1/20 0.30
ABHD5 Q8WTS1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL7169689 0.85 ALDH1A1 (0.38) ALDH1A1TSHRPAMMCL1MAOB
SCHEMBL10361556 0.84 PAM (0.38) ALDH1A1PAMMCL1MAOBMAPT
Styrene SCHEMBL465033 0.83 ALDH1A1 (0.36) ALDH1A1TSHRPAMMAPTSMN1; SMN2
Styrene SCHEMBL28318637 0.82 PAM (0.54) ALDH1A1TSHRPAMMAOBMAPT
Acrylonitrile SCHEMBL11129559 0.82 PAM (0.50) ALDH1A1PAMMCL1MAOBMAPT
Styrene SCHEMBL537154 0.81 ALDH1A1 (0.45) ALDH1A1TSHRPAMMAOBMAPT
SCHEMBL175412 0.80 ALOX15 (0.34)
SCHEMBL10431824 0.79 PAM (0.44) ALDH1A1PAMMCL1MAOBMAPT
Styrene SCHEMBL4005348 0.79 ALDH1A1 (0.40) ALDH1A1TSHRMCL1NPC1MAPT
Acrylonitrile SCHEMBL4949601 0.78 PAM (0.53) ALDH1A1PAMMCL1MAOBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3035122-B1 Method for fine line manufacturing ATOTECH DEUTSCHLAND GMBH (DE) 2019-03-20 EP disclosed
EP-3035122-A1 Method for fine line manufacturing ATOTECH Deutschland GmbH (DE) 2016-06-22 EP disclosed