Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 8/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.46 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5376189 | 0.79 | FKBP1A (0.48) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL7433188 | 0.74 | FKBP1A (0.59) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL5369696 | 0.69 | FKBP1A (0.66) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL5364010 | 0.69 | FKBP1A (0.64) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL30611182 | 0.67 | LMNA (0.57) | KDM4EALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL5376185 | 0.67 | FKBP1A (0.49) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL28332971 | 0.67 | FKBP1A (0.41) | FKBP1AMTORFKBP4FKBP5RIPK1 | |
| SCHEMBL30675171 | 0.66 | GPR119 (0.53) | RIPK1KDM4EALDH1A1BLMALOX15 | |
| SCHEMBL27703992 | 0.66 | GPR119 (0.53) | RIPK1KDM4EALDH1A1BLMALOX15 | |
| SCHEMBL14883447 | 0.65 | ALDH1A1 (0.60) | KDM4EALDH1A1BLMALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7253169-B2 | Aza compounds, pharmaceutical compositions and methods of use | GLIAMED, INC. (US) | 2007-08-07 | — | — | US | claimed |
| WO-2001079177-A1 | CYCLIC DIAZA COMPOUNDS FOR TREATING NEURODEGENERATIVE DISORDERS | GPI NIL HOLDINGS, INC. (US) | 2001-10-25 | — | — | WO | claimed |
| WO-2001079177-A1 | CYCLIC DIAZA COMPOUNDS FOR TREATING NEURODEGENERATIVE DISORDERS | GPI NIL HOLDINGS, INC. (US) | 2001-10-25 | — | — | WO | disclosed |