Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.56 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27828327 | 1.00 | LOXL2 (0.56) | LOXL2CYP4A11TSHRCYP4F2MAPT | |
| SCHEMBL27328687 | 0.86 | LOXL2 (0.59) | LOXL2CYP4A11TSHRCYP4F2MAPT | |
| SCHEMBL2692900 | 0.86 | LDHA (0.62) | LOXL2CYP4A11TSHRCYP4F2MAPT | |
| SCHEMBL7511335 | 0.83 | CYP4A11 (0.57) | LOXL2CYP4A11TSHRCYP4F2MAPT | |
| SCHEMBL23582892 | 0.83 | LOXL2 (0.56) | LOXL2CYP4A11TSHRCYP4F2MAPT | |
| SCHEMBL13577833 | 0.83 | LOXL2 (0.56) | LOXL2CYP4A11TSHRCYP4F2MAPT | |
| SCHEMBL22751983 | 0.83 | LOXL2 (0.56) | LOXL2CYP4A11TSHRCYP4F2MAPT | |
| SCHEMBL4588604 | 0.83 | LOXL2 (0.56) | LOXL2CYP4A11TSHRCYP4F2MAPT | |
| SCHEMBL2559396 | 0.82 | KMT2A (0.53) | TSHRMAPTSLC7A5MEN1KMT2A | |
| SCHEMBL1768596 | 0.81 | SLC7A5 (0.68) | LOXL2CYP4A11MAPTTDP1SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7205435-B2 | Type B botulism toxin inhibitors | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2007-04-17 | — | — | US | disclosed |
| US-20040176333-A1 | Type b botulism toxin inhibitors | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2004-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176333-A1 | Type b botulism toxin inhibitors | GZMB, CFB, MAOB | LOXL2 1975/4885CYP4A11 373/4885TSHR 2624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.