SCHEMBL5372849

SCHEMBL5372849

Brc1cccc(Oc2ccccc2)c1Oc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.44
LTA4H P09960 1/20 0.44
ALDH1A1 P00352 3/20 0.43
HPGD P15428 1/20 0.43
KMT2A Q03164 2/20 0.42
LMNA P02545 1/20 0.42
GAA P10253 1/20 0.42
DPP4 P27487 1/20 0.42
NPSR1 Q6W5P4 1/20 0.41
HRH1 P35367 1/20 0.40
CTNNB1 P35222 1/20 0.40
KDM4E B2RXH2 1/20 0.39
GLA P06280 1/20 0.39
MAPT P10636 1/20 0.39
THRA P10827 1/20 0.39
THRB P10828 1/20 0.39
SLC6A2 P23975 2/20 0.39
SLC6A4 P31645 2/20 0.39
RIPK1 Q13546 1/20 0.39
HTT P42858 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6900858 0.86 ALDH1A1 (0.48) TSHRLTA4HALDH1A1KMT2ALMNA
SCHEMBL9780873 0.84 LTA4H (0.55) TSHRLTA4HALDH1A1HPGDKMT2A
SCHEMBL130304 0.82 LTA4H (0.52) TSHRLTA4HALDH1A1HPGDKMT2A
SCHEMBL9273369 0.82 TSHR (0.52) TSHRLTA4HALDH1A1HPGDKMT2A
SCHEMBL29494593 0.81 TSHR (0.46) TSHRLTA4HALDH1A1HPGDKMT2A
SCHEMBL573706 0.81 TSHR (0.46) TSHRLTA4HALDH1A1HPGDKMT2A
SCHEMBL28416915 0.80 TSHR (0.50) TSHRLTA4HALDH1A1HPGDKMT2A
SCHEMBL11816942 0.80 LTA4H (0.57) TSHRLTA4HALDH1A1HPGDKMT2A
SCHEMBL9275082 0.80 TSHR (0.50) TSHRLTA4HALDH1A1HPGDKMT2A
SCHEMBL4859489 0.80 LTA4H (0.50) TSHRLTA4HALDH1A1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11080543-A None JP disclosed
CN-116096801-A Flame retardant polymer composition free of antimony trioxide 朗盛公司 2023-05-09 CN disclosed
JP-2007297319-A 1,3-BIS(AMINOPHENOXY)-5-(PHENYLETHYNYL)BENZENE DERIVATIVE AND METHOD FOR PRODUCING THE SAME WAKAYAMA SEIKA KOGYO KK 2007-11-15 JP disclosed
JP-H1180543-A FLAME-RETARDED RESIN COMPOSITION TORAY IND INC 1999-03-26 JP disclosed