SCHEMBL537337

SCHEMBL537337

[c]1c(C=Cc2ccccc2)ccc2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RELA Q04206 1/20 0.47
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
KDM4E B2RXH2 2/20 0.42
LMNA P02545 1/20 0.42
PKM P14618 1/20 0.42
NFE2L2 Q16236 3/20 0.38
MAOB P27338 3/20 0.38
CYP19A1 P11511 2/20 0.38
MAOA P21397 2/20 0.38
ACHE P22303 1/20 0.38
PDGFRB P09619 1/20 0.37
PDGFRA P16234 1/20 0.37
PPARG P37231 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
CHAT P28329 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL537336 1.00 RELA (0.47) RELANPC1RAB9AKDM4ELMNA
SCHEMBL8658634 0.90 CYP2A6 (0.32) RELAALDH1A1
SCHEMBL294570 0.78 CYP2A6 (0.31) MEN1KMT2A
SCHEMBL294569 0.78 CYP2A6 (0.31) MEN1KMT2A
SCHEMBL6546451 0.77 RELA (0.47) RELANPC1RAB9AKDM4ELMNA
SCHEMBL294356 0.75 ALDH1A1 (0.33) KDM4EPKMMEN1KMT2AALDH1A1
SCHEMBL3848992 0.74 NFE2L2 (0.52) RELALMNANFE2L2MAOBCYP19A1
SCHEMBL3848997 0.74 NFE2L2 (0.52) RELALMNANFE2L2MAOBCYP19A1
SCHEMBL6408377 0.74 BCHE (0.30) ACHE
SCHEMBL6839884 0.74 BCHE (0.30) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10243145-B2 Organic electroluminescence device and organic light emitting medium IDEMITSU KOSAN CO., LTD. (JP) 2019-03-26 US disclosed
US-20180212152-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC LIGHT EMITTING MEDIUM IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-9960358-B2 Organic electroluminescence device and organic light emitting medium IDEMITSU KOSAN CO., LTD. (JP) 2018-05-01 US disclosed
US-20170301863-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC LIGHT EMITTING MEDIUM IDEMITSU KOSAN CO., LTD. (JP) 2017-10-19 US disclosed
US-9728727-B2 Organic electroluminescence device and organic light emitting medium IDEMITSU KOSAN CO., LTD. (JP) 2017-08-08 US disclosed
EP-2199361-B2 Organic electroluminescent devices and organic luminescent medium IDEMITSU KOSAN CO (JP) 2016-06-15 EP disclosed
EP-2295519-B1 ORGANIC ELECTROLUMINESCENT DEVICES AND ORGANIC LUMINESCENT MEDIUM IDEMITSU KOSAN CO (JP) 2016-05-18 EP disclosed
US-9343682-B2 Organic electroluminescence device and organic light emitting medium IDEMITSU KOSAN CO., LTD. (JP) 2016-05-17 US disclosed
US-20150287929-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC LIGHT EMITTING MEDIUM IDEMITSU KOSAN CO., LTD. (JP) 2015-10-08 US disclosed
EP-1541657-B2 ORGANIC ELECTROLUMINESCENT DEVICES AND ORGANIC LUMINESCENT MEDIUM IDEMITSU KOSAN CO (JP) 2014-03-05 EP disclosed
US-6534199-B1 Exhibits excellent heat resistance, long life and high efficiency, emits bluish light; one compound selected from the group of monostyryl, distyryl, tristyryl, tetrastyryl derivatives containing amine and an anthracene derivative IDEMITSU KOSAN CO., LTD. (JP) 2003-03-18 US disclosed
CN-1366792-A Organic electroluminescent device and organic light-emitting medium IDEMITSU KOSAN CO (JP) 2002-08-28 CN disclosed
US-20020098379-A1 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. 2002-07-25 US disclosed
US-20020048688-A1 Organic electroluminescence device and organic light emitting medium IDEMITSU KOSAN CO., LTD. (JP) 2002-04-25 US disclosed
EP-1191822-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC LUMINESCENT MEDIUM IDEMITSU KOSAN CO., LTD. (JP) 2002-03-27 EP disclosed
EP-1167488-A1 ORGANIC ELECTROLUMINESCENCE AND ORGANIC LUMINOUS MEDIUM IDEMITSU KOSAN COMPANY LIMITED (JP) 2002-01-02 EP disclosed
CN-1322232-A Organic electroluminescent device and organic light-emitting medium IDEMITSU KOSAN CO (JP) 2001-11-14 CN disclosed
EP-0648805-A1 1,3,4-Thiadiazole curing systems for chlorine containing polymers R.T. VANDERBILT COMPANY, Inc. (US) 1995-04-19 EP disclosed
EP-0643101-A1 Curing systems for halogenated elastomers R.T. VANDERBILT COMPANY, Inc. (US) 1995-03-15 EP disclosed
US-5391621-A Storage stability R. T. VANDERBILT COMPANY, INC. (US) 1995-02-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10243145-B2 Organic electroluminescence device and organic light emitting medium TRPA1, EPM2A, KCNN2 RELA 1364/4885NPC1 4096/4885RAB9A 2987/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.