SCHEMBL537433

SCHEMBL537433

CC(C)(C)CCCCCCCCCCCC=O

nearest known ligand 0.52

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
FAAH O00519 2/20 0.46
TRPV1 Q8NER1 2/20 0.46
HIF1A Q16665 1/20 0.45
ACLY P53396 1/20 0.40
ALDH1A1 P00352 1/20 0.35
TDP1 Q9NUW8 2/20 0.31
FFAR1 O14842 1/20 0.31
CPT2 P23786 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19294461 1.00 TSHR (0.52) TSHRFAAHTRPV1HIF1AACLY
SCHEMBL16491137 1.00 TSHR (0.52) TSHRFAAHTRPV1HIF1AACLY
SCHEMBL1781960 1.00 TSHR (0.52) TSHRFAAHTRPV1HIF1AACLY
SCHEMBL1824574 1.00 TSHR (0.52) TSHRFAAHTRPV1HIF1AACLY
SCHEMBL12189609 1.00 TSHR (0.52) TSHRFAAHTRPV1HIF1AACLY
SCHEMBL1783238 1.00 TSHR (0.52) TSHRFAAHTRPV1HIF1AACLY
SCHEMBL1784550 0.97 TSHR (0.48) TSHRFAAHTRPV1HIF1AACLY
Ammonia Solution, Strong SCHEMBL29011533 0.95 TSHR (0.46) TSHRFAAHTRPV1HIF1AACLY
Iodide SCHEMBL28870826 0.92 TSHR (0.44) TSHRFAAHTRPV1HIF1AACLY
SCHEMBL1784079 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 482 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3109254-B1 CROSSLINKED NUCLEOSIDE AND NUCLEOTIDE UNIV OSAKA (JP) 2018-04-11 EP claimed
WO-2024135721-A1 METHOD FOR PRODUCING PRODUCTION INTERMEDIATE, PRODUCTION INTERMEDIATE THEREOF, AND METHOD FOR PRODUCING CROSSLINKED ARTIFICIAL NUCLEIC ACID INTERMEDIATE BY USING SAME 田辺三菱製薬株式会社 2024-06-27 WO disclosed
WO-2024101446-A1 MODIFIED NUCLEOSIDE HAVING GUANIDINO STRUCTURE IN BRIDGED PART AND METHOD FOR PRODUCING OLIGONUCLEOTIDE USING SAME ルクサナバイオテク株式会社 2024-05-16 WO disclosed
CN-112513062-B Oligonucleotide-containing small cell lung cancer therapeutic agent 国立大学法人大阪大学 2024-05-10 CN disclosed
US-20240148775-A1 OLIGONUCLEOTIDE FOR INDUCING N-EXON SKIPPING DURING REST MRNA PRECURSOR PROCESSING OSAKA UNIVERSITY (JP) 2024-05-09 US disclosed
CN-117964673-A Bridged artificial nucleic acid ALNA 田边三菱制药株式会社 2024-05-03 CN disclosed
CN-117964674-A Bridged artificial nucleic acid ALNA 田边三菱制药株式会社 2024-05-03 CN disclosed
US-11939421-B2 Or relating to curing agents HEXCEL COMPOSITES LIMITED (GB) 2024-03-26 US disclosed
US-11879052-B2 Curatives HEXCEL COMPOSITES LIMITED (GB) 2024-01-23 US disclosed
US-11866705-B2 Small cell lung cancer therapeutic agent containing oligonucleotide Osaka Univerity (JP) 2024-01-09 US disclosed
EP-0795326-A1 OCULAR TENSION DEPRESSANT SANKYO COMPANY LIMITED (JP) 1997-09-17 EP disclosed
CN-1157286-A N,N-dimethyl-1-t-butoxycarbonyl-4-phenylpiperidine-4-carboxamide SANKYO CO (JP) 1997-08-20 CN disclosed
EP-0776893-A1 Azaheterocyclic compounds having tachykinin receptor antagonist activity; Nk1 and NK2 SANKYO COMPANY LIMITED (JP) 1997-06-04 EP disclosed
CN-1148809-A intraocular pressure lowering agent SANKYO CO (JP) 1997-04-30 CN disclosed
US-5556864-A TREATMENT OF CIRCULATORY DISEASES AND PSYCHOSIS SANKYO COMPANY, LIMITED (JP) 1996-09-17 US disclosed
CN-1102640-A Alpha, omega-diarylalkane derivatives, their preparation and their use in the treatment and prevention of circulatory and psychiatric disorders SANKYO CO (JP) 1995-05-17 CN disclosed
EP-0600717-A1 Phenoxyalkylamines, -pyrrolidines and -piperidines for the treatment and prevention of circulatory diseases and psychosis SANKYO COMPANY LIMITED (JP) 1994-06-08 EP disclosed
EP-0156100-B1 3-SUBSTITUTED HYDROXYPENTANEDIOIC ACIDS, -HEMIESTERS OR -ANHYDRIDES G.D. Searle & Co. (US) 1989-12-27 EP disclosed
US-4554359-A 3-Substituted pentanedioic acids and derivatives thereof G. D. SEARLE & CO. (US) 1985-11-19 US disclosed
EP-0156100-A2 3-Substituted hydroxypentanedioic acids, -hemiesters or -anhydrides G.D. Searle & Co. (US) 1985-10-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240148775-A1 OLIGONUCLEOTIDE FOR INDUCING N-EXON SKIPPING DURING REST MRNA PRECURSOR PROCESSING UPF1, RBM17, NSUN2 TSHR 3099/4885FAAH 4761/4885TRPV1 3587/4885
US-11939421-B2 Or relating to curing agents FABP4, RARA, ADIPOR1 TSHR 4021/4885FAAH 263/4885TRPV1 935/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.