SCHEMBL537511

SCHEMBL537511

CCCC[Si](CCCC)(CCCC)OC

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.37
TSHR P16473 2/20 0.35
THRB P10828 1/20 0.33
EPHX1 P07099 1/20 0.31
ADRB2 P07550 1/20 0.30
ADRB1 P08588 1/20 0.30
ADRB3 P13945 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL703497 0.97 LMNA (0.35) LMNATSHRTHRBEPHX1
SCHEMBL703661 0.97 LMNA (0.35) LMNATSHRTHRBEPHX1
SCHEMBL707567 0.97 LMNA (0.35) LMNATSHRTHRBEPHX1
SCHEMBL3481732 0.94 LMNA (0.34) LMNATSHRTHRB
SCHEMBL16497600 0.94 LMNA (0.39) LMNATSHRTHRBEPHX1
SCHEMBL3481472 0.94 LMNA (0.34) LMNATSHRTHRB
SCHEMBL613246 0.91 LMNA (0.40) LMNATSHRTHRBEPHX1
SCHEMBL19356773 0.88 TSHR (0.44) LMNATSHRTHRBEPHX1
SCHEMBL3482907 0.88 LMNA (0.34) LMNATSHRTHRB
SCHEMBL612829 0.88 TSHR (0.44) LMNATSHRTHRBEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 569 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119627216-A Electrolyte for inhibiting circulating gas production of sodium ion battery and preparation method and application thereof 湖南法恩莱特新能源科技有限公司 2025-03-14 CN claimed
WO-2024232632-A1 TRANSITION METAL SUPPORTED CATALYST WITH IMPROVED HYDROGENATION ACTIVITY AND USE THEREOF 한양대학교 산학협력단 2024-11-14 WO claimed
CN-118909171-A Solid catalyst component for olefin polymerization reaction, preparation method and application thereof 中国石油化工股份有限公司 2024-11-08 CN claimed
CN-115155113-B Structure for organic silicon defoamer and synthesis method thereof 佛山市南海大田化学有限公司 2023-09-29 CN claimed
CN-115105868-B Organic silicon defoamer and preparation method thereof 佛山市南海大田化学有限公司 2023-07-18 CN claimed
CN-115105868-A Organic silicon defoaming agent and preparation method thereof 佛山市南海大田化学有限公司 2022-09-27 CN claimed
CN-114106458-A Irradiation modified PP melt-blown material and composite forming process thereof 中核同辐(长春)辐射技术有限公司 2022-03-01 CN claimed
US-11059920-B2 Process for producing high cis-1,4-polydiene with lanthanide-based catalyst compositions BRIDGESTONE CORPORATION (JP) 2021-07-13 US claimed
WO-2021118145-A1 METHOD FOR PREPARING OLEFIN-BASED POLYMER BY GAS-PHASE POLYMERIZATION 한화솔루션 주식회사 2021-06-17 WO claimed
US-20190169330-A1 Process For Producing High Cis-1,4-Polydiene With Lanthanide-Based Catalyst Compositions BRIDGESTONE CORPORATION (JP) 2019-06-06 US claimed
US-20060189163-A1 Method of forming thick silica-based film NISSAN CHEMICAL INDUSTRIES LTD. (JP) 2006-08-24 US claimed
US-20050288525-A1 Reagents for asymmetric allylation, aldol, and tandem aldol and allylation reactions NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2005-12-29 US claimed
WO-2005090282-A1 ANDROGEN RECEPTOR MODULATOR COMPOUNDS AND METHODS LIGAND PHARMACEUTICALS INCORPORATED (US) 2005-09-29 WO claimed
CN-1220627-C Method for manufacturing hydrophobic colloidal silica DSM IP N V (NL) 2005-09-28 CN claimed
EP-1480988-A1 REAGENTS FOR ASYMMETRIC ALLYLATION, ALDOL, AND TANDEM ALDOL AND ALLYLATION REACTIONS The Trustees of Columbia University in the City of New York (US) 2004-12-01 EP claimed
EP-1252095-B1 METHOD FOR MANUFACTURING HYDROPHOBIC COLLOIDAL SILICA DSM IP ASSETS BV (NL) 2004-11-10 EP claimed
WO-2003074534-A9 REAGENTS FOR ASYMMETRIC ALLYLATION, ALDOL, AND TANDEM ALDOL AND ALLYLATION REACTIONS UNIV COLUMBIA (US) 2003-11-20 WO claimed
WO-2003074534-A1 REAGENTS FOR ASYMMETRIC ALLYLATION, ALDOL, AND TANDEM ALDOL AND ALLYLATION REACTIONS THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2003-09-12 WO claimed
CN-1429178-A Method for manufacturing hydrophobic colloidal silica DSM NV (NL) 2003-07-09 CN claimed
US-20030035888-A1 Method for manufacturing hydrophobic colloidal silica JSR CORPORATION (JP) 2003-02-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050288525-A1 Reagents for asymmetric allylation, aldol, and tandem aldol and allylation reactions AKR1C3, AKR1B10, CBR3 LMNA 1028/4885TSHR 349/4885THRB 1735/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.