Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 2/20 | 0.55 |
| ▸ | AURKA | O14965 | 3/20 | 0.53 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.51 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.48 |
| ▸ | CTSV | O60911 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | PYGL | P06737 | 1/20 | 0.47 |
| ▸ | PYGM | P11217 | 1/20 | 0.47 |
| ▸ | CDC7 | O00311 | 1/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ASPH | Q12797 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31650723 | 0.80 | SMN1; SMN2 (0.54) | MAPK10P4HTMSMN1; SMN2MAPK9EGFR | |
| SCHEMBL25389479 | 0.78 | MAPK10 (0.55) | MAPK10AURKAMAPK8PIK3CGCAMKK2 | |
| SCHEMBL4926335 | 0.78 | CAMKK2 (0.67) | AURKAMAPK8PIK3CGCAMKK2P4HTM | |
| SCHEMBL29501419 | 0.78 | MAPK10 (0.55) | MAPK10AURKAMAPK8PIK3CGCAMKK2 | |
| SCHEMBL23337477 | 0.78 | ACVRL1 (0.55) | MAPK10AURKAMAPK8P4HTMSMN1; SMN2 | |
| SCHEMBL5442670 | 0.74 | AURKA (0.67) | AURKAMAPK8PIK3CGCAMKK2AKR1C3 | |
| SCHEMBL11644754 | 0.73 | AKR1C3 (0.68) | AKR1C3AKR1C2SMN1; SMN2CTSVCTSL | |
| SCHEMBL27588527 | 0.73 | ALDH1A1 (0.64) | MAPK10AURKASMN1; SMN2EGFRKDM4E | |
| SCHEMBL9427888 | 0.72 | MAPT (0.62) | MAPK10AURKAMAPK8SMN1; SMN2EGFR | |
| SCHEMBL31580872 | 0.72 | BRAF (0.48) | MAPK10MAPK8SMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007138110-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | claimed |