Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 6/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1357755 | 0.84 | CA2 (0.49) | ALDH1A1TSHRCA2HPGDTP53 | |
| SCHEMBL6052957 | 0.81 | ALDH1A1 (0.59) | ALDH1A1TSHRCA2TP53CYP3A4 | |
| SCHEMBL774502 | 0.80 | CTDSP1 (0.38) | ALDH1A1TSHRCA2HPGDTP53 | |
| SCHEMBL13966298 | 0.79 | TSHR (0.39) | ALDH1A1TSHRCA2HPGDTP53 | |
| SCHEMBL1355043 | 0.78 | ALDH1A1 (0.37) | ALDH1A1TSHRCA2HPGDTP53 | |
| SCHEMBL774725 | 0.77 | TSHR (0.41) | ALDH1A1TSHRCA2HPGD | |
| SCHEMBL8372836 | 0.76 | MGLL (0.56) | ALDH1A1 | |
| SCHEMBL23045301 | 0.76 | ALDH1A1 (0.33) | ALDH1A1TSHRCA2TP53CYP3A4 | |
| SCHEMBL11459365 | 0.75 | ALDH1A1 (0.33) | ALDH1A1CA2 | |
| Acetone SCHEMBL20503787 | 0.75 | ALDH1A1 (0.58) | ALDH1A1TSHRHPGDTP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564243-B1 | Polyphenylene ether-graft-orthoester copolymer blends | GEN ELECTRIC (US) | 2001-02-28 | — | — | EP | claimed |
| EP-0659834-B1 | Polycarbonate compositions comprising thermoplastic olefin copolymers | GEN ELECTRIC (US) | 1999-09-29 | — | — | EP | claimed |
| EP-0499717-B1 | Ethylenically unsaturated cyclic ortho esters | GEN ELECTRIC (US) | 1998-04-01 | — | — | EP | claimed |
| EP-0747375-A1 | Method for making orthoester monomers | GENERAL ELECTRIC COMPANY (US) | 1996-12-11 | — | — | EP | claimed |
| EP-0659834-A2 | Polycarbonate compositions comprising thermoplastic olefin copolymers | GENERAL ELECTRIC COMPANY (US) | 1995-06-28 | — | — | EP | claimed |
| US-5391616-A | A blends consisting a graft copolymer having an orthoester or orthocarbonate functionalized addition monomers and an acid, acid anhydride or thiol functionalized monomers; semi-gloss, tensile strength, high viscosity, elongation | GENERAL ELECTRIC COMPANY (US) | 1995-02-21 | — | — | US | claimed |
| EP-0564244-A1 | The functionalization of polyphenylene ethers with graftable orthoesters | GENERAL ELECTRIC COMPANY (US) | 1993-10-06 | — | — | EP | claimed |
| EP-0564243-A1 | Polyphenylene ether-graft-orthoester copolymer blends | GENERAL ELECTRIC COMPANY (US) | 1993-10-06 | — | — | EP | claimed |
| US-5247006-A | Blends with polyesters, polyamides or polyolefins | GENERAL ELECTRIC COMPANY (US) | 1993-09-21 | — | — | US | claimed |
| US-5177146-A | Ortho Ester Grafted Olefin Copolymer | GENERAL ELECTRIC COMPANY (US) | 1993-01-05 | — | — | US | claimed |
| US-5171866-A | To compatibilize blends; forming epdm graft polymers | GENERAL ELECTRIC COMPANY (US) | 1992-12-15 | — | — | US | claimed |
| EP-0499717-A1 | Ethylenically unsaturated cyclic ortho esters | GENERAL ELECTRIC COMPANY (US) | 1992-08-26 | — | — | EP | claimed |
| US-7297812-B2 | Process for preparing unsaturated, cyclic orthoesters | DEGUSSA AG (DE) | 2007-11-20 | — | — | US | disclosed |
| EP-1242537-B1 | POLY(PHENYLENE ETHER)-POLYAMIDE RESIN BLENDS, METHOD OF MANUFACTURE | GEN ELECTRIC (US) | 2007-03-07 | — | — | EP | disclosed |
| US-20060281930-A1 | Process for preparing unsaturated, cyclic orthoesters | DEGUSSA AG (DE) | 2006-12-14 | — | — | US | disclosed |
| EP-1714964-A1 | Preparation of unsaturated cyclic orthoesters | Degussa GmbH (DE) | 2006-10-25 | — | — | EP | disclosed |
| EP-0496116-A1 | Polymers of ethylenically unsaturated cyclic ortho esters | GENERAL ELECTRIC COMPANY (US) | 1992-07-29 | — | — | EP | disclosed |
| US-5132361-A | Reacting with polymers capable of nucleophilic substitution | GENERAL ELECTRIC COMPANY (US) | 1992-07-21 | — | — | US | disclosed |
| EP-0487678-A1 | THERMOPLASTIC ELASTOMERS AND METHOD FOR MAKING. | GEN ELECTRIC (US) | 1992-06-03 | — | — | EP | disclosed |
| WO-1991019765-A1 | THERMOPLASTIC ELASTOMERS AND METHOD FOR MAKING | GENERAL ELECTRIC COMPANY (US) | 1991-12-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060281930-A1 | Process for preparing unsaturated, cyclic orthoesters | NR1H3, OSBP2, AGL | ALDH1A1 2645/4885TSHR 1806/4885CA2 3330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.