Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11580300 | 0.91 | MAPT (0.51) | MAPTTDP1KDM4EPTGER4CYP1A2 | |
| SCHEMBL11137910 | 0.91 | MAPT (0.45) | MAPTTDP1KDM4EPTGER4CYP1A2 | |
| SCHEMBL11142434 | 0.87 | SERPINE1 (0.52) | MAPTTDP1KDM4EPTGER4CYP1A2 | |
| SCHEMBL5386629 | 0.86 | TDP1 (0.56) | MAPTTDP1KDM4EPTGER4CYP1A2 | |
| SCHEMBL12211371 | 0.85 | RAB9A (0.47) | MAPTTDP1KDM4ELMNARAB9A | |
| SCHEMBL1927097 | 0.83 | LMNA (0.62) | MAPTTDP1KDM4EPTGER4CYP1A2 | |
| SCHEMBL11581098 | 0.83 | CYP1A2 (0.65) | MAPTTDP1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11146233 | 0.83 | KDM4E (0.57) | TDP1KDM4ELMNANPC1RAB9A | |
| SCHEMBL9761032 | 0.81 | ALDH1A1 (0.67) | MAPTKDM4ECYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11681698 | 0.78 | MAPT (0.54) | MAPTTDP1KDM4EPTGER4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7309389-B2 | Preparation of azo colorants in microreactors and their use in electrophotographic toners and developers, powder coatings, ink jet inks and electronic medias | CLARIANT FINANCE (BVI) LIMITED (VG) | 2007-12-18 | — | — | US | disclosed |
| US-20070213516-A1 | Process For Producing High-Purity Azo Dyes | HOELLEIN VOLKER | 2007-09-13 | — | — | US | disclosed |
| US-7135266-B2 | Preparation of azo colorants in microreactors and their use in electrophotographic toners and developers, powder coatings, ink jet inks and electronic medias | CLARIANT FINANCE (BVI) LIMITED (VG) | 2006-11-14 | — | — | US | disclosed |
| US-20060228640-A1 | Preparation of azo colorants in microreactors and their use in electrophotographic toners and developers, powder coatings, ink jet inks and electronic medias | CLARIANT FINANCE (BVI) LIMITED | 2006-10-12 | — | — | US | disclosed |
| US-20060042117-A1 | Method and device for carrying out chemical and physical methods | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2006-03-02 | — | — | US | disclosed |
| CN-1210350-C | Method and device for continuously controlling the redox in azo coupling | CLARANT GMBH (DE) | 2005-07-13 | — | — | CN | disclosed |
| US-20040131507-A1 | Adjustment of concentration of reactants; rotating electrodes transverse to fluid flow; process control | SAITMACHER KLAUS (DE) | 2004-07-08 | — | — | US | disclosed |
| CN-1492910-A | Method and device for continuous redox adjustment in azoic couplings | 科莱恩有限公司 | 2004-04-28 | — | — | CN | disclosed |
| US-20030083410-A1 | Preparation of azo colorants in microreactors and their use in electrophotographic toners and developers, powder coatings, ink jet inks and electronic medias | CLARIANT FINANCE ( BVI) LIMITED | 2003-05-01 | — | — | US | disclosed |
| US-6548647-B2 | Spraying coupling components in solution or suspension to collide in reactor chamber, then pressurizing to remove; useful for offset printing inks | CLARIANT GMBH (DE) | 2003-04-15 | — | — | US | disclosed |
| US-6469147-B2 | DIAZOTIZATION | CLARIANT FINANCE (BVI) LIMITED (VG) | 2002-10-22 | — | — | US | disclosed |
| US-6437104-B1 | DIAZOTIZATION OF AROMATIC AMINE, AZO COUPLING TO FORM AN AZOCARBOXYLIC ACID OR AZODICARBOXYLIC ACID, FORMATION OF AN AZOCARBONYL CHLORIDE OR AZODICARBONYL DICHLORIDE AND CONDENSATION WITH AROMATIC DIAMINE | CLARIANT GMBH (DE) | 2002-08-20 | — | — | US | disclosed |
| US-20020058794-A1 | Preparation of disazo condensation pigments in microreactors | CLARIANT INTERNATIONAL LTD. | 2002-05-16 | — | — | US | disclosed |
| US-20020055619-A1 | Process for preparing azo colorants | CLARIANT GMBH | 2002-05-09 | — | — | US | disclosed |
| US-20010029294-A1 | Preparation of azo colorants in microreactors | CLARIANT INTERNATIONAL LTD. | 2001-10-11 | — | — | US | disclosed |
| US-4392999-A | COLORFAST BROWN, RED AND ORANGE | CIBA-GEIGY CORPORATION (US) | 1983-07-12 | — | — | US | disclosed |
| US-4229344-A | Monazo pigments containing hydroxynaphthoylaminobenzimidazalone radical | CIBA-GEIGY CORPORATION (US) | 1980-10-21 | — | — | US | disclosed |
| US-4070353-A | FOR PLASTICS AND PRINTING INKS, YELLOW TO ORANGE SHADES | CIBA-GEIGY CORPORATION (US) | 1978-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020058794-A1 | Preparation of disazo condensation pigments in microreactors | DDT, DDC, DKC1 | MAPT 1876/4885TDP1 3347/4885KDM4E 902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.