SCHEMBL538055

SCHEMBL538055

CSCC[C@H](N)C(=O)NCC(=O)O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
PTGS2 P35354 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
RNPEP Q9H4A4 1/20 0.44
CTSC P53634 1/20 0.43
FNTA P49354 3/20 0.42
FNTB P49356 3/20 0.42
PGGT1B P53609 2/20 0.42
ARG1 P05089 1/20 0.41
ARG2 P78540 1/20 0.41
PTGS1 P23219 1/20 0.40
GSTK1 Q9Y2Q3 1/20 0.40
MMP2 P08253 3/20 0.40
ECE1 P42892 1/20 0.40
DPP7 Q9UHL4 2/20 0.39
MME P08473 1/20 0.39
ACE P12821 1/20 0.39
CPA1 P15085 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL538056 1.00 ALDH1A1 (0.44) ALDH1A1LMNAMAPTPTGS2TDP1
Hydrochloric Acid SCHEMBL28446971 0.98 ALDH1A1 (0.43) ALDH1A1LMNAMAPTPTGS2TDP1
Hydrochloric Acid SCHEMBL28446972 0.98 ALDH1A1 (0.43) ALDH1A1LMNAMAPTPTGS2TDP1
SCHEMBL29350823 0.94 MMP2 (0.41) ALDH1A1LMNAMAPTPTGS2TDP1
SCHEMBL30052506 0.88 TSHR (0.47) LMNAFNTAFNTBPGGT1BPTGS1
SCHEMBL30052913 0.88 METAP2 (0.43) ALDH1A1LMNAMAPTPTGS2TDP1
SCHEMBL8000185 0.87 FNTA (0.48) FNTAFNTBPGGT1BPTGS1GSTK1
SCHEMBL8000193 0.87 FNTA (0.48) FNTAFNTBPGGT1BPTGS1GSTK1
SCHEMBL30052468 0.85 FNTA (0.43) ALDH1A1LMNAMAPTPTGS2TDP1
SCHEMBL30590002 0.85 PTGS1 (0.42) ALDH1A1LMNAMAPTPTGS2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 277 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724610-A2 HIGH THROUGHPUT SCREEN FOR GENETIC VARIANTS ASSOCIATED WITH SHORT STATURE BioMarin Pharmaceutical Inc. (US) 2026-04-15 EP claimed
EP-4013453-B1 HYDROPHOBIC PEPTIDE SALTS FOR EXTENDED RELEASE COMPOSITIONS BIOMARIN PHARM INC (US) 2026-03-04 EP claimed
US-12514906-B2 Use of C-type natriuretic peptide variants to treat skeletal dysplasia BIOMARIN PHARMACEUTICAL INC. (US) 2026-01-06 US claimed
US-20250170217-A1 C-TYPE NATRIURETIC PEPTIDE VARIANTS TO TREAT SKELETAL DYSPLASIA IN CHILDREN BIOMARIN PHARMACEUTICAL INC. 2025-05-29 US claimed
WO-2025076498-A1 TREATMENT OF OSTEOGENESIS IMPERFECTA WITH C-TYPE NATRIURETIC PEPTIDE AND ANALOGS THEREOF BIOMARIN PHARMACEUTICAL INC. (US) 2025-04-10 WO claimed
US-12233106-B2 C-type natriuretic peptide variants to treat skeletal dysplasia in children BIOMARIN PHARMACEUTICAL INC. (US) 2025-02-25 US claimed
US-12214015-B2 Use of c-type natriuretic peptide variants to treat osteoarthritis BIOMARIN PHARMACEUTICAL INC. (US) 2025-02-04 US claimed
US-20250032576-A1 CNP Therapy BIOMARIN PHARMACEUTICAL INC. 2025-01-30 US claimed
WO-2024254405-A2 HIGH THROUGHPUT SCREEN FOR GENETIC VARIANTS ASSOCIATED WITH SHORT STATURE BIOMARIN PHARMACEUTICAL INC. (US) 2024-12-12 WO claimed
CN-119104653-A Method for detecting impurities in compound amino acid injection 四川太平洋药业有限责任公司 2024-12-10 CN claimed
WO-2023283657-A1 C-TYPE NATRIURETIC PEPTIDE VARIANTS TO TREAT SKELETAL DYSPLASIA IN CHILDREN BIOMARIN PHARMACEUTICAL INC. (US) 2023-01-12 WO claimed
EP-4019038-A2 USE OF C-TYPE NATRIURETIC PEPTIDE VARIANTS TO TREAT OSTEOARTHRITIS BioMarin Pharmaceutical Inc. (US) 2022-06-29 EP claimed
CN-108472336-B Use of C-type natriuretic peptide variants for the treatment of skeletal dysplasia 生物马林药物股份有限公司 2022-05-31 CN claimed
US-20220160836-A1 USE OF C-TYPE NATRIURETIC PEPTIDE VARIANTS TO TREAT OSTEOARTHRITIS BIOMARIN PHARMACEUTICAL INC. 2022-05-26 US claimed
US-20160374380-A1 SALTY TASTE ENHANCER T. HASEGAWA CO., LTD. (JP) 2016-12-29 US claimed
EP-0357784-B1 A FEED COMPOSITION FOR CULTURING FISHES AND SHELLFISHES KYOWA HAKKO KOGYO CO., LTD. (JP) 1992-09-02 EP claimed
EP-0357784-A1 A FEED COMPOSITION FOR CULTURING FISHES AND SHELLFISHES. KYOWA HAKKO KOGYO KK (JP) 1990-03-14 EP claimed
WO-1989006497-A1 A FEED COMPOSITION FOR CULTURING FISHES AND SHELLFISHES KYOWA HAKKO KOGYO CO., LTD. (JP) 1989-07-27 WO claimed
US-4095000-A AMINO ACIDS AND DERIVATIVES, POLYHYDROXY COMPOUNDS, NUTRIENTS, HYDROLYSIS Brenner, Max (CH) 1978-06-13 US claimed
US-3959519-A Fortification of food materials with a methionine source E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-05-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250032576-A1 CNP Therapy CNP, NPPA, NPR1 ALDH1A1 4498/4885LMNA 897/4885MAPT 4742/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.