Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.49 |
| ▸ | PDE9A | O76083 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | GRK2 | P25098 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989732 | 0.82 | GAA (0.52) | HSD17B10GAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL5380552 | 0.80 | XDH (0.53) | HSD17B10KMT2AMEN1ALDH1A1CLK4 | |
| SCHEMBL7992854 | 0.73 | GPR84 (0.41) | KMT2AMEN1ROCK2ROCK1PRKCA | |
| SCHEMBL3830998 | 0.73 | MEN1 (0.54) | PDE9AKMT2AMEN1ALDH1A1ROCK2 | |
| SCHEMBL7989847 | 0.73 | CDC7 (0.43) | CLK4ROCK2ROCK1PRKCAGRK2 | |
| SCHEMBL7996288 | 0.72 | MTNR1A (0.46) | CYP3A4CYP2D6CLK4ROCK2ROCK1 | |
| SCHEMBL7996305 | 0.72 | CDC7 (0.45) | KMT2AMEN1ALDH1A1CDC7 | |
| SCHEMBL7993806 | 0.72 | FABP1 (0.45) | GAATSHRCLK4ROCK2PRKCA | |
| SCHEMBL7991079 | 0.72 | ALOX5 (0.41) | HSD17B10KMT2AMEN1ALDH1A1CLK4 | |
| SCHEMBL5375269 | 0.71 | CDC7 (0.43) | CDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001070727-A1 | 2-(ARYLALKYLAMINO)PYRIMIDONE DERIVATIVES AND 2-(HETEROARYLALKYLAMINO)PYRIMIDONE DERIVATIVES | SANOFI-SYNTHELABO (FR) | 2001-09-27 | — | — | WO | claimed |