Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.40 |
| ▸ | CDC7 | O00311 | 3/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | GRK2 | P25098 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989847 | 0.84 | CDC7 (0.43) | ROCK2CDC7GSK3BMAP4K4PIM1 | |
| SCHEMBL5380552 | 0.83 | XDH (0.53) | ROCK2CDC7GSK3BMAP4K4PIM1 | |
| SCHEMBL7993806 | 0.81 | FABP1 (0.45) | ROCK2CDC7GSK3BMAP4K4PIM1 | |
| SCHEMBL7996305 | 0.79 | CDC7 (0.45) | CDC7KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL7993164 | 0.76 | ROCK2 (0.42) | ROCK2CDC7GSK3BMAP4K4PIM1 | |
| SCHEMBL7989732 | 0.76 | GAA (0.52) | ROCK2CDC7GSK3BMAP4K4PIM1 | |
| SCHEMBL7978376 | 0.76 | ROCK2 (0.41) | ROCK2CDC7GSK3BMAP4K4PIM1 | |
| SCHEMBL7993013 | 0.75 | ROCK2 (0.41) | ROCK2CDC7GSK3BMAP4K4PIM1 | |
| SCHEMBL7989807 | 0.72 | CDC7 (0.39) | ROCK2CDC7GSK3BROCK1MEN1 | |
| SCHEMBL7990975 | 0.72 | HSD17B10 (0.49) | ROCK2CDC7CLK4GRK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001070727-A1 | 2-(ARYLALKYLAMINO)PYRIMIDONE DERIVATIVES AND 2-(HETEROARYLALKYLAMINO)PYRIMIDONE DERIVATIVES | SANOFI-SYNTHELABO (FR) | 2001-09-27 | — | — | WO | disclosed |