Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5373002 | 0.98 | CA2 (0.47) | CA2ALDH1A1PKMHTR6SMN1; SMN2 | |
| SCHEMBL5386071 | 0.93 | CA2 (0.46) | CA2ALDH1A1PKMHTR6SMN1; SMN2 | |
| SCHEMBL19175488 | 0.87 | G6PD (0.47) | CA2SMN1; SMN2ALOX5CA1CA9 | |
| SCHEMBL5377515 | 0.86 | HTR6 (0.47) | CA2ALDH1A1PKMHTR6SMN1; SMN2 | |
| SCHEMBL5374401 | 0.81 | CA2 (0.42) | CA2ALDH1A1SMN1; SMN2GAAMAPT | |
| SCHEMBL561582 | 0.81 | ALDH1A1 (0.52) | CA2ALDH1A1PKMHTR6SMN1; SMN2 | |
| SCHEMBL20597342 | 0.81 | ALDH1A1 (0.46) | CA2ALDH1A1PKMSMN1; SMN2GAA | |
| SCHEMBL5382807 | 0.80 | CA2 (0.43) | CA2ALDH1A1SMN1; SMN2GAAMAPT | |
| SCHEMBL3477025 | 0.79 | KCNH2 (0.49) | ALDH1A1GAAMAPTMEN1HTT | |
| SCHEMBL11783489 | 0.79 | KCNH2 (0.49) | ALDH1A1GAAMAPTMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7202359-B2 | Azaoxa heterocyclic compound and method of preparing the same | CHANG CHUN PLASTICS CO., LTD. (TW) | 2007-04-10 | — | — | US | disclosed |
| CN-1234706-C | Nitrogen-oxygen heterocyclic compound and preparation method thereof | CHANGCHUN ARTIFICIAL RESIN FAC (CN) | 2006-01-04 | — | — | CN | disclosed |
| US-20050085634-A1 | Azaoxa heterocyclic compound and method of preparing the same | CHANG CHUN PLASTICS CO., LTD. (TW) | 2005-04-21 | — | — | US | disclosed |
| CN-1490318-A | Nitrogen-oxygen heterocyclic compound and preparation method thereof | 长春人造树脂厂股份有限公司 | 2004-04-21 | — | — | CN | disclosed |
| US-20040068084-A1 | Azaoxa heterocyclic compound and method of preparing the same | CHANG CHUN PLASTICS CO., LTD. (TW) | 2004-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040068084-A1 | Azaoxa heterocyclic compound and method of preparing the same | AOX1, KDM1A, BMI1 | CA2 4496/4885ALDH1A1 81/4885PKM 3622/4885 |
| US-20050085634-A1 | Azaoxa heterocyclic compound and method of preparing the same | AOX1, KDM1A, BMI1 | CA2 4419/4885ALDH1A1 116/4885PKM 3546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.