SCHEMBL5381887

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6371474	0.87	MAPT (0.33)	ABL1ABCB1BCRMAPTLMNA
	SCHEMBL6351754	0.86	ABL1 (0.35)	ABL1ABCB1BCRRELATRPA1
	SCHEMBL5383989	0.86	ABL1 (0.32)	ABL1ABCB1BCRRELA
	SCHEMBL15048521	0.83	RELA (0.54)	ABL1ABCB1BCRRELATRPA1
	Styrene SCHEMBL4582900	0.82	ALDH1A1 (0.54)	RELATRPA1ALDH1A1TSHRMAPT
	SCHEMBL131860	0.82	ALDH1A1 (0.50)	TRPA1ALDH1A1TSHRMAPTLMNA
	SCHEMBL6037016	0.81	ELANE (0.48)	ABL1ABCB1BCRRELAALDH1A1
	4-Vinylphenol SCHEMBL3329747	0.80	MEN1 (0.44)	ABL1ABCB1BCRTRPA1ALDH1A1
	SCHEMBL5550084	0.80	MAPT (0.39)	ABL1ABCB1BCRTRPA1ALDH1A1
	SCHEMBL15347286	0.78	MAPT (0.45)	ALDH1A1MAPTMEN1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.