Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 5/20 | 0.38 |
| ▸ | PPARA | Q07869 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7511335 | 0.83 | CYP4A11 (0.57) | CA12CA1CA2CA9CA14 | |
| SCHEMBL14011593 | 0.83 | CYP4A11 (0.47) | SLC7A5CA12CA1CA2CA9 | |
| SCHEMBL7428977 | 0.81 | CYP4A11 (0.45) | SLC7A5CA12CA1CA2CA9 | |
| SCHEMBL5373775 | 0.80 | SLC7A5 (0.43) | SLC7A5CA12CA1CA2CA9 | |
| SCHEMBL2211024 | 0.80 | CA1 (0.46) | SLC7A5CA12CA1CA2CA9 | |
| SCHEMBL14966328 | 0.80 | HDAC1 (0.50) | SLC7A5CA12CA1CA2CA9 | |
| SCHEMBL10518208 | 0.79 | ALDH1A1 (0.47) | PPARAMEN1KMT2A | |
| SCHEMBL3484081 | 0.79 | MMP2 (0.50) | SLC7A5CA1CA2CYP4A11CYP4F2 | |
| SCHEMBL3790673 | 0.78 | NR1H4 (0.51) | CA12CA1CA2CA9CA14 | |
| SCHEMBL2690871 | 0.78 | LDHA (0.53) | SLC7A5CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7205435-B2 | Type B botulism toxin inhibitors | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2007-04-17 | — | — | US | disclosed |
| US-20040176333-A1 | Type b botulism toxin inhibitors | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2004-09-09 | — | — | US | disclosed |
| EP-1377601-A2 | TYPE B BOTULISM TOXIN INHIBITORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2004-01-07 | — | — | EP | disclosed |
| WO-2002083716-A2 | TYPE B BOTULISM TOXIN INHIBITORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2002-10-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176333-A1 | Type b botulism toxin inhibitors | GZMB, CFB, MAOB | SLC7A5 3234/4885CA12 3128/4885CA1 3453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.