Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8344730 | 0.91 | NPC1 (0.37) | NPC1RAB9ASMN1; SMN2HPGDPOLB | |
| SCHEMBL8344663 | 0.83 | MAPT (0.51) | NPC1RAB9ASMN1; SMN2HPGDTSHR | |
| SCHEMBL20199977 | 0.79 | ALDH1A1 (0.49) | NPC1RAB9ASMN1; SMN2POLBMAPT | |
| SCHEMBL5383549 | 0.75 | EGFR (0.42) | HPGDTSHRMAPTHSD17B10RECQL | |
| SCHEMBL17191283 | 0.73 | BACE1 (0.47) | SMN1; SMN2HDAC8HTT | |
| SCHEMBL25798559 | 0.73 | HDAC8 (0.50) | NPC1RAB9ASMN1; SMN2TSHRHDAC8 | |
| SCHEMBL13448174 | 0.73 | SLC2A1 (0.54) | NPC1RAB9ASMN1; SMN2HPGDPOLB | |
| SCHEMBL23017937 | 0.72 | CCR5 (0.50) | NPC1RAB9ASMN1; SMN2MAPTHTT | |
| SCHEMBL20359857 | 0.72 | MAPT (0.49) | NPC1RAB9ASMN1; SMN2MRGPRX4HDAC8 | |
| SCHEMBL2519601 | 0.72 | LMNA (0.54) | RAB9ASMN1; SMN2MAPTCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932675-A | Free-radical chain transfer polymerization process | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1999-08-03 | — | — | US | disclosed |
| US-5874511-A | CHAIN TRANSFER | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-02-23 | — | — | US | disclosed |