Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3266022 | 0.74 | NPC1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL5387209 | 0.74 | HTR7 (0.32) | — | |
| Hydrochloric Acid SCHEMBL29479988 | 0.69 | PNMT (0.50) | — | |
| Hydrochloric Acid SCHEMBL618215 | 0.69 | PNMT (0.50) | — | |
| Hydrochloric Acid SCHEMBL10513406 | 0.68 | PNMT (0.49) | — | |
| Hydrochloric Acid SCHEMBL5179338 | 0.68 | ALDH1A1 (0.32) | — | |
| Fluoride Ion SCHEMBL1131318 | 0.66 | PNMT (0.50) | — | |
| Bromide SCHEMBL7878842 | 0.66 | PNMT (0.50) | — | |
| SCHEMBL5838693 | 0.66 | PNMT (0.50) | — | |
| Hydrochloric Acid SCHEMBL21245428 | 0.66 | ALDH1A1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7259219-B2 | Low molecular weight copolymer of ethylene and vinyl aromatic monomer and uses thereof | DOW GLOBAL TECHNOLOGIES INC. (US) | 2007-08-21 | — | — | US | disclosed |
| EP-1495059-B1 | LOW MOLECULAR WEIGHT COPOLYMER OF ETHYLENE AND VINYL AROMATIC MONOMER AND USES THEREOF | DOW GLOBAL TECHNOLOGIES INC (US) | 2006-05-24 | — | — | EP | disclosed |
| US-20050165192-A1 | Low molecular weight copolymer of ethylene and vinyl aromatic monomer and uses thereof | DOW GLOBAL TECHNOLOGIES, INC. | 2005-07-28 | — | — | US | disclosed |
| EP-1495059-A1 | LOW MOLECULAR WEIGHT COPOLYMER OF ETHYLENE AND VINYL AROMATIC MONOMER AND USES THEREOF | DOW GLOBAL TECHNOLOGIES INC. (US) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003087178-A1 | LOW MOLECULAR WEIGHT COPOLYMER OF ETHYLENE AND VINYL AROMATIC MONOMER AND USES THEREOF | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-10-23 | — | — | WO | disclosed |
| US-6329479-B1 | POLYMERIZING AROMATIC VINYL COMPOUND AND OLEFIN IN PRESENCE OF POLYMERIZATION CATALYST COMPRISING A TRANSITION METAL COMPOUND AND COCATALYST | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2001-12-11 | — | — | US | disclosed |