SCHEMBL9686002

SCHEMBL9686002

CC(CCl)(O[SiH3])c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.41
TAAR1 Q96RJ0 2/20 0.39
ALDH1A1 P00352 2/20 0.39
ALOX15 P16050 1/20 0.39
TSHR P16473 1/20 0.36
CYP2C19 P33261 1/20 0.35
HIF1A Q16665 1/20 0.35
SLC6A2 P23975 1/20 0.34
KCNN4 O15554 3/20 0.33
ESR1 P03372 2/20 0.33
ESR2 Q92731 2/20 0.33
KMT2A Q03164 2/20 0.33
CYP3A4 P08684 1/20 0.33
MEN1 O00255 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5387344 0.81 MAPK1 (0.43) MAPK1TAAR1ALDH1A1ALOX15TSHR
SCHEMBL3481487 0.78 MAPK1 (0.40) MAPK1TAAR1ALDH1A1ALOX15TSHR
SCHEMBL15302558 0.78 TAAR1 (0.52) MAPK1TAAR1ALDH1A1ALOX15CYP2C19
SCHEMBL15848465 0.75 ALDH1A1 (0.44) MAPK1TAAR1ALDH1A1ALOX15TSHR
SCHEMBL3481672 0.75 MAPK1 (0.38) MAPK1TAAR1ALDH1A1ALOX15KCNN4
SCHEMBL5180283 0.75 MAPK1 (0.38) MAPK1TAAR1ALDH1A1ALOX15KCNN4
SCHEMBL1262885 0.74 TSHR (0.39) MAPK1TAAR1ALDH1A1ALOX15TSHR
SCHEMBL10518614 0.72 MAPT (0.47) MAPK1TAAR1ALDH1A1ALOX15CYP2C19
SCHEMBL4079894 0.71 TSHR (0.36) MAPK1TAAR1ALDH1A1ALOX15TSHR
SCHEMBL1502452 0.70 TAAR1 (0.58) MAPK1TAAR1ALDH1A1ALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5096991-A Monomer from dihydroxy aromatic compound and haloalkylsilanol, elasticity, strength SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-03-17 US disclosed