Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6048376 | 0.85 | KCNN4 (0.39) | KCNN4RAB9AUSP2CA1CA2 | |
| SCHEMBL168026 | 0.80 | ALDH1A1 (0.53) | KCNN4RAB9AUSP2PAX8CYP1A1 | |
| SCHEMBL7929536 | 0.80 | KCNN4 (0.44) | KCNN4RAB9AUSP2CA1CA2 | |
| SCHEMBL8560690 | 0.79 | USP2 (0.43) | KCNN4RAB9AUSP2CYP19A1RORC | |
| SCHEMBL10578903 | 0.79 | KCNN4 (0.35) | KCNN4RAB9AUSP2CA1CA2 | |
| SCHEMBL6048383 | 0.79 | LMNA (0.36) | KCNN4RAB9AUSP2CA1CA2 | |
| SCHEMBL6556363 | 0.79 | LMNA (0.36) | KCNN4RAB9AUSP2CA1CA2 | |
| SCHEMBL25119775 | 0.78 | KCNN4 (0.42) | KCNN4RAB9AUSP2CA1CA2 | |
| SCHEMBL3158793 | 0.78 | TSHR (0.50) | KCNN4RAB9AUSP2CA1CA2 | |
| SCHEMBL11623312 | 0.76 | CA1 (0.42) | KCNN4CA1CA2CA9CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0201031-B1 | (METH)ACRYLIC ESTERS AND THEIR USE | BAYER AG (DE) | 1989-08-02 | — | — | EP | claimed |
| US-4665217-A | DENTAL FILLERS AND COATINGS | BAYER AKTIENGESELLSCHAFT (DE) | 1987-05-12 | — | — | US | claimed |
| EP-0201031-A2 | (Meth)acrylic esters and their use | BAYER AG (DE) | 1986-11-12 | — | — | EP | claimed |
| US-20070270618-A1 | Fluorine-containing bisphenols, their preparation, their precursors and intermediates, and use of the fluorine-containing bisphenols | MARHOLD ALBRECHT | 2007-11-22 | — | — | US | disclosed |
| US-7268260-B2 | Fluorine-containing bisphenols, their preparation, their precursors and intermediates, and use of the fluorine-containing bisphenols | LANXESS DEUTSCHLAND GMBH (DE) | 2007-09-11 | — | — | US | disclosed |
| US-20060266985-A1 | Fluorine-containing bisphenols, their preparation, their precursors and intermediates, and use of the fluorine-containing bisphenols | MARHOLD ALBRECHT | 2006-11-30 | — | — | US | disclosed |
| US-7112704-B2 | Fluorine-containing bisphenols, their preparation, their precursors and intermediates, and use of the fluorine-containing bisphenols | BAYER AKTIENGESELLSCHAFT (DE) | 2006-09-26 | — | — | US | disclosed |
| US-20050230669-A1 | coupling 4-halobenzotrichlorides in the presence of copper and tertiary amine solvents, to form chemical intermediates for liquid crystals, flameproofing, polyesters, polyethers or polycarbonates | LANXESS DEUTSCHLAND GMBH (DE) | 2005-10-20 | — | — | US | disclosed |
| US-6936739-B2 | Fluorine-containing bisphenols, their preparation, their precursors and intermediates, and use of the fluorine-containing bisphenols | BAYER AKTIENGESELLSCHAFT (DE) | 2005-08-30 | — | — | US | disclosed |
| US-20030009060-A1 | Fluorine-containing bisphenols, their preparation, their precursors and intermediates, and use of the fluorine-containing bisphenols | LANXESS DEUTSCHLAND GMBH (DE) | 2003-01-09 | — | — | US | disclosed |
| EP-1262471-A2 | Fluorine-containing bisphenols, their preparation, intermediates towards their preparation, and their use | BAYER AG (DE) | 2002-12-04 | — | — | EP | disclosed |
| EP-0201031-B1 | (METH)ACRYLIC ESTERS AND THEIR USE | BAYER AG (DE) | 1989-08-02 | — | — | EP | disclosed |
| US-4665217-A | DENTAL FILLERS AND COATINGS | BAYER AKTIENGESELLSCHAFT (DE) | 1987-05-12 | — | — | US | disclosed |
| EP-0201031-A2 | (Meth)acrylic esters and their use | BAYER AG (DE) | 1986-11-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050230669-A1 | coupling 4-halobenzotrichlorides in the presence of copper and tertiary amine solvents, to form chemical intermediates for liquid crystals, flameproofing, polyesters, polyethers or polycarbonates | CYP4F2, CYP4F12, CYP4F3 | KCNN4 585/4885RAB9A 3844/4885USP2 813/4885 |
| US-20060266985-A1 | Fluorine-containing bisphenols, their preparation, their precursors and intermediates, and use of the fluorine-containing bisphenols | CYP4F2, AFF4, CYP4F3 | KCNN4 929/4885RAB9A 3506/4885USP2 1315/4885 |
| US-20070270618-A1 | Fluorine-containing bisphenols, their preparation, their precursors and intermediates, and use of the fluorine-containing bisphenols | CYP4F2, AFF4, CYP4F3 | KCNN4 929/4885RAB9A 3506/4885USP2 1315/4885 |
| US-20030009060-A1 | Fluorine-containing bisphenols, their preparation, their precursors and intermediates, and use of the fluorine-containing bisphenols | CYP2F1, HNF4A, FLI1 | KCNN4 845/4885RAB9A 3429/4885USP2 1627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.