Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | RORA | P35398 | 1/20 | 0.35 |
| ▸ | RORB | Q92753 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1284428 | 0.90 | PGK1 (0.40) | HSD11B1NR1H2NR1H3PGK1PGK2 | |
| SCHEMBL9621272 | 0.83 | KIF11 (0.46) | CYP2C9NR1H2NR1H3PGK1PGK2 | |
| SCHEMBL9508396 | 0.81 | ESR1 (0.56) | RAB9ACYP3A4PGK1PGK2ESR1 | |
| SCHEMBL1357633 | 0.80 | ALDH1A1 (0.50) | HSD11B1CYP19A1KCNN4CYP2C9CYP2C19 | |
| SCHEMBL4982243 | 0.79 | KIF11 (0.46) | RAB9AHSD11B1CYP3A4NPSR1NR1H2 | |
| SCHEMBL2776477 | 0.79 | MLYCD (0.50) | CYP19A1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL5388697 | 0.79 | KCNN4 (0.44) | USP2RAB9AHSD11B1CYP19A1KCNN4 | |
| SCHEMBL8021367 | 0.75 | NR1H2 (0.58) | USP2RAB9ARORCNR1H2NR1H3 | |
| SCHEMBL11410841 | 0.74 | KIF11 (0.52) | RAB9ACYP3A4RORCNR1H2NR1H3 | |
| SCHEMBL1134055 | 0.74 | ALDH1A1 (0.44) | NR1H2NR1H3PGK1PGK2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1050833-A | — | — | None | — | — | JP | disclosed |
| US-5827611-A | Multilayered thermoplastic article with special properties | HOECHST CELANESE CORP (US) | 1998-10-27 | — | — | US | disclosed |
| EP-0467935-B1 | TRANSPARENT THERMOPLASTIC MOULDING MATERIAL CONSISTING OF ESTERS OF 2,3-DIFLUORACRYLIC ACID | HOECHST AG (DE) | 1994-12-14 | — | — | EP | disclosed |
| EP-0606598-A2 | Shaped articles of graduated refractive index exhibiting low dispersion | HOECHST CELANESE CORPORATION (US) | 1994-07-20 | — | — | EP | disclosed |
| WO-1994015005-A1 | SHAPED ARTICLES OF GRADUATED REFRACTIVE INDEX | HOECHST CELANESE CORPORATION (US) | 1994-07-07 | — | — | WO | disclosed |
| US-5283303-A | Optionally deuterated; high glass transition temperature; used in manufacture of waveguides | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-02-01 | — | — | US | disclosed |
| US-5175790-A | Waveguides for long distance transmission, high temperature continuous use | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-12-29 | — | — | US | disclosed |
| EP-0467935-A1 | TRANSPARENT THERMOPLASTIC MOULDING MATERIAL CONSISTING OF ESTERS OF 2,3-DIFLUORACRYLIC ACID. | HOECHST AG (DE) | 1992-01-29 | — | — | EP | disclosed |
| WO-1990012040-A1 | TRANSPARENT THERMOPLASTIC MOULDING MATERIAL CONSISTING OF ESTERS OF 2,3-DIFLUORACRYLIC ACID | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-10-18 | — | — | WO | disclosed |
| JP-S6450833-A | PRODUCTION OF 2,2-BIS(4-FLUOROPHENYL)HEXAFLUOROPROPANE | CENTRAL GLASS CO LTD | 1989-02-27 | — | — | JP | disclosed |