Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 3/20 | 0.54 |
| ▸ | DRD4 | P21917 | 3/20 | 0.54 |
| ▸ | DRD3 | P35462 | 3/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10605800 | 0.90 | CHRNB2 (0.54) | ACHEDRD2DRD4DRD3OPRM1 | |
| SCHEMBL6833092 | 0.79 | MAOA (0.66) | ACHEDRD2DRD4DRD3ESR1 | |
| SCHEMBL4188283 | 0.79 | MAOA (0.66) | ACHEDRD2DRD4DRD3ESR1 | |
| SCHEMBL4202026 | 0.79 | MAOA (0.66) | ACHEDRD2DRD4DRD3ESR1 | |
| SCHEMBL1576021 | 0.79 | ACHE (0.51) | ACHEDRD2DRD4DRD3MAOA | |
| SCHEMBL3645107 | 0.79 | ACHE (0.51) | ACHEDRD2DRD4DRD3MAOA | |
| SCHEMBL3855142 | 0.79 | ACHE (0.51) | ACHEDRD2DRD4DRD3OPRM1 | |
| SCHEMBL22547384 | 0.79 | ACHE (0.51) | ACHEDRD2DRD4DRD3OPRM1 | |
| SCHEMBL30896364 | 0.79 | ACHE (0.51) | ACHEDRD2DRD4DRD3MAOA | |
| SCHEMBL13853486 | 0.78 | DRD2 (0.53) | ACHEDRD2DRD4DRD3MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7294739-B1 | Basic amine esters or oleic acid and their use as anti-inflammatory or immunobodulatory agents | TEVA PHARMACAETICAL INDUSTRIES LTD. (IL) | 2007-11-13 | — | — | US | disclosed |
| US-7294739-B1 | Basic amine esters or oleic acid and their use as anti-inflammatory or immunobodulatory agents | TEVA PHARMACAETICAL INDUSTRIES LTD. (IL) | 2007-11-13 | — | — | US | disclosed |
| US-7294739-B1 | Basic amine esters or oleic acid and their use as anti-inflammatory or immunobodulatory agents | TEVA PHARMACAETICAL INDUSTRIES LTD. (IL) | 2007-11-13 | — | — | US | disclosed |
| EP-1535902-B1 | Aminoindan derivatives | TEVA PHARMA (IL) | 2007-11-07 | — | — | EP | disclosed |
| US-RE39616-E1 | Aminoindan derivatives | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2007-05-08 | — | — | US | disclosed |
| EP-1535902-A1 | Aminoindan derivatives | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2005-06-01 | — | — | EP | disclosed |
| EP-0966435-B1 | AMINOINDAN DERIVATIVES | TEVA PHARMA (IL) | 2005-04-06 | — | — | EP | disclosed |
| EP-0966435-A4 | AMINOINDAN DERIVATIVES | TEVA PHARMA (IL) | 2003-04-16 | — | — | EP | disclosed |
| US-6538025-B2 | Aminoindan derivatives | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2003-03-25 | — | — | US | disclosed |
| US-20020188020-A1 | Aminoindan derivatives | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM | 2002-12-12 | — | — | US | disclosed |
| EP-0150192-B1 | BICYCLIC BENZENOID AMINOALKYLENE ETHERS AND THIOETHERS | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1989-12-20 | — | — | EP | disclosed |
| US-4745110-A | ANTIULCER AGENTS, ANTISECRETORY AGENTS | RORER PHARMACEUTICAL CORPORATION (US) | 1988-05-17 | — | — | US | disclosed |
| US-4692445-A | ANTISECRETORY, ANTIULCEROGENIC AGENTS | RORER PHARMACEUTICAL CORPORATION (US) | 1987-09-08 | — | — | US | disclosed |
| US-4647559-A | ANTISECRETORY AND ANTIULCER AGENTS | WILLIAM H. RORER, INC. (US) | 1987-03-03 | — | — | US | disclosed |
| US-4638001-A | ANTISECRETORY, ANTIULCER AGENTS | WILLIAM H. RORER, INC. (US) | 1987-01-20 | — | — | US | disclosed |
| US-4588719-A | ANTISCERETORY AGENTS, ANTIULCER AGENTS | WILLIAM H. RORER, INC. (US) | 1986-05-13 | — | — | US | disclosed |
| EP-0150192-A4 | BICYCLIC BENZENOID AMINOALKYLENE ETHERS AND THIOETHERS. | RORER INTERNAT OVERSEAS INC (US) | 1985-09-16 | — | — | EP | disclosed |
| EP-0150192-A1 | BICYCLIC BENZENOID AMINOALKYLENE ETHERS AND THIOETHERS. | RORER INT OVERSEAS (US) | 1985-08-07 | — | — | EP | disclosed |
| US-4529723-A | Gastrointestinal disorders; antiulcer agents | WILLIAM H. RORER, INC. (US) | 1985-07-16 | — | — | US | disclosed |
| WO-1984004247-A1 | BICYCLIC BENZENOID AMINOALKYLENE ETHERS AND THIOETHERS, AND THEIR PHARMACEUTICAL USES | RORER INT OVERSEAS (US) | 1984-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020188020-A1 | Aminoindan derivatives | SNCA, HTR1A, HTR1D | ACHE 58/4885DRD2 18/4885DRD4 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.