Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | JAK1 | P23458 | 2/20 | 0.33 |
| ▸ | TYK2 | P29597 | 2/20 | 0.33 |
| ▸ | JAK3 | P52333 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20791418 | 0.67 | KDM4C (0.39) | ALOX5APFEN1 | |
| SCHEMBL16918916 | 0.67 | ALDH1A1 (0.48) | — | |
| SCHEMBL9735595 | 0.64 | KMT2A (0.56) | — | |
| SCHEMBL16156588 | 0.64 | PKM (0.54) | — | |
| SCHEMBL9991060 | 0.62 | — | — | |
| SCHEMBL15536958 | 0.62 | CA1 (0.35) | ALOX5APFEN1JAK2JAK1TYK2 | |
| SCHEMBL11823742 | 0.62 | — | — | |
| SCHEMBL15917537 | 0.61 | TRPV4 (0.46) | ALOX5APFEN1 | |
| SCHEMBL18184073 | 0.61 | — | — | |
| SCHEMBL20811834 | 0.61 | PAX8 (0.31) | JAK2JAK1TYK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2413701-A1 | SULFONYL-AZETIDIN-3-YL-METHYLAMINE AMIDE ANALOGS AS GLYT1 INHIBITORS, METHODS FOR MAKING SAME, AND USE OF SAME IN TREATING PSYCHIATRIC DISORDERS | Vanderbilt University (US) | 2012-02-08 | — | — | EP | disclosed |