Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | OPRL1 | P41146 | 14/20 | 0.52 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14502993 | 0.90 | ALDH1A1 (0.67) | ALDH1A1TSHRRAB9ANPC1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL1704549 | 0.90 | ALDH1A1 (0.49) | ALDH1A1TSHRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5381229 | 0.85 | ALDH1A1 (0.53) | ALDH1A1TSHRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5381243 | 0.85 | ALDH1A1 (0.53) | ALDH1A1TSHRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5387405 | 0.83 | ALDH1A1 (0.57) | ALDH1A1TSHRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14502995 | 0.79 | ALDH1A1 (0.80) | ALDH1A1TSHRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1704979 | 0.79 | RAB9A (0.74) | ALDH1A1TSHRRAB9ANPC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1704951 | 0.78 | RAB9A (0.73) | TSHRRAB9ANPC1SMN1; SMN2TNKS | |
| Trifluoroacetic Acid SCHEMBL5384259 | 0.77 | ALDH1A1 (0.45) | ALDH1A1TSHRRAB9ANPC1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL5384262 | 0.77 | ALDH1A1 (0.45) | ALDH1A1TSHRRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1642899-B1 | 2,4-BIS(TRIFLUOROETHOXY)PYRIDINE COMPOUND AND MEDICINE CONTAINING THE SAME | KOWA CO (JP) | 2012-08-15 | — | — | EP | disclosed |
| US-7223764-B2 | 2,4-bis (trifluoroethoxy)pyridine compound and drug containing the compound | KOWA CO., LTD. (JP) | 2007-05-29 | — | — | US | disclosed |
| EP-1642899-A1 | 2,4-BIS(TRIFLUOROETHOXY)PYRIDINE COMPOUND AND MEDICINE CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 2006-04-05 | — | — | EP | disclosed |
| US-20050020606-A1 | 2,4-Bis (trifluoroethoxy)pyridine compound and drug containing the compound | KOWA CO., LTD. (JP) | 2005-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050020606-A1 | 2,4-Bis (trifluoroethoxy)pyridine compound and drug containing the compound | ACAT2, ACAT1, CYP7A1 | ALDH1A1 586/4885TSHR 3355/4885RAB9A 855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.