Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 12/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5397952 | 0.90 | ALDH1A1 (0.58) | ALDH1A1TSHROPRL1RAB9ANPC1 | |
| Trifluoroacetic Acid SCHEMBL5384259 | 0.88 | ALDH1A1 (0.45) | ALDH1A1TSHROPRL1RAB9ANPC1 | |
| Trifluoroacetic Acid SCHEMBL5384262 | 0.88 | ALDH1A1 (0.45) | ALDH1A1TSHROPRL1RAB9ANPC1 | |
| Trifluoroacetic Acid SCHEMBL6282185 | 0.84 | RAB9A (0.60) | ALDH1A1TSHRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14502993 | 0.81 | ALDH1A1 (0.67) | ALDH1A1TSHROPRL1RAB9ANPC1 | |
| SCHEMBL5387405 | 0.77 | ALDH1A1 (0.57) | ALDH1A1TSHROPRL1RAB9ANPC1 | |
| SCHEMBL1705553 | 0.77 | ALDH1A1 (0.52) | ALDH1A1TSHROPRL1RAB9ANPC1 | |
| SCHEMBL5381243 | 0.77 | ALDH1A1 (0.53) | ALDH1A1TSHROPRL1RAB9ANPC1 | |
| SCHEMBL5381229 | 0.77 | ALDH1A1 (0.53) | ALDH1A1TSHROPRL1RAB9ANPC1 | |
| SCHEMBL1705217 | 0.73 | ALDH1A1 (0.37) | ALDH1A1TSHROPRL1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8518936-B2 | Method for preparing acid addition salts of polyacidic basic compounds | KOWA CO., LTD. (JP) | 2013-08-27 | — | — | US | disclosed |
| EP-1642899-B1 | 2,4-BIS(TRIFLUOROETHOXY)PYRIDINE COMPOUND AND MEDICINE CONTAINING THE SAME | KOWA CO (JP) | 2012-08-15 | — | — | EP | disclosed |
| EP-1598346-B1 | PROCESS FOR PRODUCING ACID ADDUCT SALT OF POLYACIDIC BASE COMPOUND | KOWA CO (JP) | 2012-04-18 | — | — | EP | disclosed |
| US-20100234599-A1 | METHOD FOR PREPARING ACID ADDITION SALTS OF POLYACIDIC BASIC COMPOUNDS | KOWA CO., LTD. (JP) | 2010-09-16 | — | — | US | disclosed |
| US-7750150-B2 | Process for producing acid adduct salt of polyacidic base compound | KOWA CO., LTD. (JP) | 2010-07-06 | — | — | US | disclosed |
| US-7223764-B2 | 2,4-bis (trifluoroethoxy)pyridine compound and drug containing the compound | KOWA CO., LTD. (JP) | 2007-05-29 | — | — | US | disclosed |
| US-20060079688-A1 | Process for producing acid adduct salt of polyacidic base compound | KOWA CO., LTD. (JP) | 2006-04-13 | — | — | US | disclosed |
| EP-1642899-A1 | 2,4-BIS(TRIFLUOROETHOXY)PYRIDINE COMPOUND AND MEDICINE CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 2006-04-05 | — | — | EP | disclosed |
| EP-1598346-A1 | PROCESS FOR PRODUCING ACID ADDUCT SALT OF POLYACIDIC BASE COMPOUND | Kowa Co., Ltd. (JP) | 2005-11-23 | — | — | EP | disclosed |
| US-20050020606-A1 | 2,4-Bis (trifluoroethoxy)pyridine compound and drug containing the compound | KOWA CO., LTD. (JP) | 2005-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234599-A1 | METHOD FOR PREPARING ACID ADDITION SALTS OF POLYACIDIC BASIC COMPOUNDS | PGA5, NAAA, CA6 | ALDH1A1 1557/4885TSHR 4702/4885OPRL1 3977/4885 |
| US-20060079688-A1 | Process for producing acid adduct salt of polyacidic base compound | CA5B, ASIC1, NAAA | ALDH1A1 1334/4885TSHR 4829/4885OPRL1 3599/4885 |
| US-20050020606-A1 | 2,4-Bis (trifluoroethoxy)pyridine compound and drug containing the compound | ACAT2, ACAT1, CYP7A1 | ALDH1A1 586/4885TSHR 3355/4885OPRL1 4402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.