Water

Water

SCHEMBL5398689

C=CSC=C.C=CSC=C.O

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL50200 0.94
Sulfur Dioxide SCHEMBL28089880 0.80
Sulfur Dioxide SCHEMBL27819214 0.80
Vinyl Ether SCHEMBL28090587 0.74
Ethylene Glycol SCHEMBL2955063 0.74
Ethylene Glycol SCHEMBL7850509 0.71 TSHR (0.36)
SCHEMBL8061934 0.69
1,4-Butanediol SCHEMBL7850531 0.69 SMN1; SMN2 (0.35)
SCHEMBL12896054 0.67
SCHEMBL2554926 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1589308-A Phosphorus-containing carboxylic acid derivatives, process for preparations thereof and flame retardant NOF CORP (JP) 2005-03-02 CN claimed
CN-1168144-A (Meth) acrylic syrup, process for preparing the same, and process for preparing molding material contg. (meth) acrylic syrup NIPPON CATALYTIC CHEM IND (JP) 1997-12-17 CN claimed
CN-106604979-A Processed hydrocarbon-containing mixture and method and system for making the same CM全球系统有限责任公司 2017-04-26 CN disclosed
CN-105837554-A Synthesis method for 1,3,5-trithio heterocyclic hexane derivative 河北科技大学 2016-08-10 CN disclosed
CN-102585166-B Active resin composition, method of surface mounting and printed substrate YAMAHIDE CHEMISTRY CO., LTD. (JP) 2016-06-01 CN disclosed
EP-1433832-B1 PHOSPHORUS-CONTAINING CARBOXYLIC ACID DERIVATIVES,PROCESS FOR PREPARATION THEREOF, AND FLAME RETARDANTS NOF CORP (JP) 2013-11-13 EP disclosed
CN-102585166-A Active resin composition, surface mounting method and printed wiring board SAN EI KAGAKU CO 2012-07-18 CN disclosed
CN-102482473-A Photocurable fluoropolymer composition ASAHI GLASS CO LTD 2012-05-30 CN disclosed
CN-101145005-B Image forming apparatus and image forming process RICOH CO LTD 2011-05-11 CN disclosed
CN-100396739-C Ink jet ink composition for color filter, method for preparing ink composition and method for preparing color filter DAINIPPON PRINTING CO LTD (JP) 2008-06-25 CN disclosed
CN-101145005-A Image forming apparatus and image forming process RICOH KK (JP) 2008-03-19 CN disclosed
CN-1247651-C Resin composition for optical-semiconductor encapsulation SUMITOMO CHEMICAL CO (JP) 2006-03-29 CN disclosed
CN-1589308-A Phosphorus-containing carboxylic acid derivatives, process for preparations thereof and flame retardant NOF CORP (JP) 2005-03-02 CN disclosed
US-20040249028-A1 Phosphorus-containing carboxylic acid derivatives process for preparations thereof and flame retardant NOF CORPORATION (JP) 2004-12-09 US disclosed
EP-1433832-A1 PHOSPHORUS&amp;minus;CONTAINING CARBOXYLIC ACID DERIVATIVES&amp;comma; PROCESS FOR PREPARATION THEREOF&amp;comma; AND FLAME RETARDANTS NOF CORPORATION (JP) 2004-06-30 EP disclosed
CN-1507462-A Resin composition for optical-semiconductor encapsulation ס�ѻ�ѧ��ҵ��ʽ���� 2004-06-23 CN disclosed
CN-1152058-C (Meth) acrylic syrup, process for preparing the same, and process for preparing molding material contg. (meth) acrylic syrup ��ʽ�����ձ���ý 2004-06-02 CN disclosed
CN-1392204-A Ink jet ink composition for color filter, method for preparing ink composition and method for preparing color filter DAINIPPON PRINTING CO LTD (JP) 2003-01-22 CN disclosed
CN-1388780-A Thermo-sensitive recording type lithographical block material, method of making up lithographical block, and lithographical block made up by the making up method LABO CO LTD (JP) 2003-01-01 CN disclosed
CN-1168144-A (Meth) acrylic syrup, process for preparing the same, and process for preparing molding material contg. (meth) acrylic syrup NIPPON CATALYTIC CHEM IND (JP) 1997-12-17 CN disclosed