Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 4/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA7 | P43166 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4233485 | 0.94 | ACHE (0.45) | ACHEALDH1A1MITFLMNATP53 | |
| SCHEMBL301752 | 0.86 | CA1 (0.44) | ACHEALDH1A1TP53MAPTPGR | |
| SCHEMBL5397188 | 0.82 | PGR (0.43) | ALDH1A1PGRMEN1KMT2ACA1 | |
| SCHEMBL14428501 | 0.79 | TNFSF11 (0.55) | MAPTTSHRPGRMEN1KMT2A | |
| SCHEMBL8595488 | 0.77 | PGR (0.50) | ALDH1A1TP53MAPTTSHRPGR | |
| SCHEMBL14428500 | 0.75 | PDE4A (0.41) | ALDH1A1LMNATP53MAPTPGR | |
| SCHEMBL6224983 | 0.75 | PGR (0.45) | ALDH1A1LMNAMAPTPGRMEN1 | |
| SCHEMBL10401817 | 0.74 | KDM4E (0.56) | ACHEALDH1A1MITFMAPTGAA | |
| SCHEMBL6554850 | 0.73 | PDE4B (0.37) | ALDH1A1LMNAMAPTPGRMEN1 | |
| SCHEMBL6553226 | 0.73 | PDE4B (0.37) | ALDH1A1LMNAMAPTPGRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185057-A1 | Novel Indanone Compounds | SYMRISE GMBH & CO. KG (DE) | 2007-08-09 | — | — | US | disclosed |
| US-20070185057-A1 | Novel Indanone Compounds | SYMRISE GMBH & CO. KG (DE) | 2007-08-09 | — | — | US | disclosed |
| US-7208142-B2 | Indanylidene compounds | SYMRISE GMBH & CO. KG (DE) | 2007-04-24 | — | — | US | disclosed |
| EP-1466892-A1 | Novel indanylidene compounds | Symrise GmbH & Co. KG (DE) | 2004-10-13 | — | — | EP | disclosed |
| EP-1341752-B1 | NOVEL INDANYLIDENE COMPOUNDS | SYMRISE GMBH & CO KG (DE) | 2004-08-04 | — | — | EP | disclosed |
| EP-1000950-B1 | Novel indanylidene compounds | HOFFMANN LA ROCHE (CH) | 2004-02-25 | — | — | EP | disclosed |
| CN-1473146-A | Novel indanylidene compounds | ��������ķ������ | 2004-02-04 | — | — | CN | disclosed |
| EP-1341752-A1 | NOVEL INDANYLIDENE COMPOUNDS | HAARMANN & REIMER GMBH (DE) | 2003-09-10 | — | — | EP | disclosed |
| US-20020143203-A1 | Novel indanylidene compounds | SYMRISE GMBH & CO. KG (DE) | 2002-10-03 | — | — | US | disclosed |
| US-6416746-B1 | ULTRAVIOLET RAY AND LIGHT SCREENING MATERIAL GRAFTED TO SILANE, OLIGOSILOXANE, OR POLYSILOXANE WITH IMPROVED SOLUBILITY AND LITTLE PENETRATION; FOR USE IN COSMETICS | ROCHE VITAMINS INC. | 2002-07-09 | — | — | US | disclosed |
| WO-2002038537-A1 | NOVEL INDANYLIDENE COMPOUNDS | HAARMANN & REIMER GMBH (DE) | 2002-05-16 | — | — | WO | disclosed |
| EP-1000950-A2 | Novel indanylidene compounds | F. HOFFMANN-LA ROCHE AG (CH) | 2000-05-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185057-A1 | Novel Indanone Compounds | CUTA, NISCH, TYR | ACHE 2591/4885ALDH1A1 434/4885MITF 102/4885 |
| US-20020143203-A1 | Novel indanylidene compounds | CUTA, NISCH, ERCC4 | ACHE 2498/4885ALDH1A1 373/4885MITF 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.