Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL5402982

CCCCO.O=C(O)C(F)(F)F

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.55
FAAH O00519 8/20 0.48
CES1 P23141 6/20 0.46
CES2 O00748 3/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
HSD17B10 Q99714 2/20 0.46
CYP1A2 P05177 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
FUCA1 P04066 1/20 0.44
LMNA P02545 2/20 0.43
TSHR P16473 1/20 0.43
EPHX1 P07099 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL28259283 0.98 ALDH1A1 (0.52) ALDH1A1FAAHCES1CES2MEN1
1-Hexanol SCHEMBL7731082 0.91 LMNA (0.59) ALDH1A1FAAHCES1CES2MEN1
Octanol SCHEMBL374162 0.91 LMNA (0.59) ALDH1A1FAAHCES1CES2MEN1
Nonanol SCHEMBL271357 0.91 LMNA (0.59) ALDH1A1FAAHCES1CES2MEN1
1-Heptanol SCHEMBL22557209 0.91 LMNA (0.59) ALDH1A1FAAHCES1CES2MEN1
Trifluoroacetic Acid SCHEMBL28259282 0.90 FAAH (0.54) FAAHCES1CES2MEN1KMT2A
Trifluoroacetic Acid SCHEMBL5880385 0.87 FAAH (0.56) FAAHCES1CES2MEN1KMT2A
Trifluoroacetic Acid SCHEMBL3369969 0.87 FAAH (0.42) FAAHCES1CES2MEN1KMT2A
Trifluoroacetic Acid SCHEMBL29581339 0.87 FAAH (0.54) FAAHCES1CES2MEN1KMT2A
Trifluoroacetic Acid SCHEMBL3273685 0.87 FAAH (0.61) ALDH1A1FAAHCES1CES2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103269704-B Heterocyclic compound and its purposes 西建卡尔有限责任公司 2018-07-06 CN disclosed
CN-101643470-B Alkyl ether derivatives or salts thereof TOYAMA CHEMICAL CO LTD 2012-08-01 CN disclosed
CN-101643470-A Alkyl ether derivatives or salts thereof TOYAMA CHEMICAL CO LTD JP 2010-02-10 CN disclosed
CN-100500662-C Alkyl ether derivative or salt thereof TOYAMA CHEMICAL CO LTD (JP) 2009-06-17 CN disclosed
US-7262228-B2 Photoinitiator systems with anthracene-based electron donors for curing cationically polymerizable resins CURATORS OF THE UNIVERSITY OF MISSOURI (US) 2007-08-28 US disclosed
CN-1324018-C Oligopeptides and compositions containing them as cathepsin S inhibitors AVENTIS PHARMA INC (US) 2007-07-04 CN disclosed
US-20050113477-A1 Photoinitiator systems with anthracene-based electron donors for curing cationically polymerizable resins 3M DEUTSCHLAND GMBH (DE) 2005-05-26 US disclosed
CN-1585757-A Oligopeptides and compositions containing them as cathepsin S inhibitors AVENTIS PHARMA INC (US) 2005-02-23 CN disclosed
CN-1571786-A Alkyl ether derivative or salt thereof TOYAMA CHEMICAL CO LTD (JP) 2005-01-26 CN disclosed
EP-0038629-A1 Virazole derivatives, process for their preparation and use as antiviral agents BEECHAM GROUP PLC (GB) 1981-10-28 EP disclosed