Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL3369969

CCCO.O=C(O)C(F)(F)F

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FAAH O00519 9/20 0.42
CES1 P23141 7/20 0.41
CES2 O00748 5/20 0.41
MEN1 O00255 1/20 0.41
CYP1A2 P05177 1/20 0.41
KMT2A Q03164 1/20 0.41
HSD17B10 Q99714 1/20 0.41
FUCA1 P04066 1/20 0.40
EPHX1 P07099 1/20 0.37
FFAR3 O14843 2/20 0.36
HDAC3 O15379 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC8 Q9BY41 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL28259282 0.92 FAAH (0.54) FAAHCES1CES2MEN1CYP1A2
Trifluoroacetic Acid SCHEMBL10447938 0.88 FAAH (0.35) FAAHCES1CES2MEN1CYP1A2
Trifluoroacetic Acid SCHEMBL3794549 0.88 FAAH (0.40) FAAHCES1CES2MEN1CYP1A2
Trifluoroacetic Acid SCHEMBL15711042 0.88 FAAH (0.46) FAAHCES1CES2MEN1CYP1A2
Trifluoroacetic Acid SCHEMBL30324569 0.88 FAAH (0.40) FAAHCES1CES2MEN1CYP1A2
Trifluoroacetic Acid SCHEMBL281599 0.88 FAAH (0.40) FAAHCES1CES2MEN1CYP1A2
Trifluoroacetic Acid SCHEMBL5402982 0.87 ALDH1A1 (0.55) FAAHCES1CES2MEN1CYP1A2
Trifluoroacetic Acid SCHEMBL21924385 0.85 FAAH (0.39) FAAHCES1CES2MEN1CYP1A2
Trifluoroacetic Acid SCHEMBL6909668 0.85 FAAH (0.39) FAAHCES1CES2MEN1CYP1A2
Trifluoroacetic Acid SCHEMBL27681955 0.85 FAAH (0.39) FAAHCES1CES2MEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117007691-A Method for detecting content of thermosensitive active protein in liquid milk 上海市质量监督检验技术研究院 2023-11-07 CN claimed
US-5011777-A DNA expression construct ONCOGEN (US) 1991-04-30 US claimed
US-4963485-A ANTITUMOR AGENTS ONCOGEN 1990-10-16 US claimed
EP-0210233-A4 BRAIN DERIVABLE POLYPEPTIDE FACTORS AND ANTIBODIES. ONCOGEN (US) 1989-11-07 EP claimed
EP-0210233-A1 BRAIN DERIVABLE POLYPEPTIDE FACTORS AND ANTIBODIES ONCOGEN (US) 1987-02-04 EP claimed
WO-1986004239-A1 BRAIN DERIVABLE POLYPEPTIDE FACTORS AND ANTIBODIES ONCOGEN (US) 1986-07-31 WO claimed
JP-3172183-A None JP disclosed
US-20240425505-A1 TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2024-12-26 US disclosed
US-12110290-B2 Triazolopyridinyl compounds as kinase inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2024-10-08 US disclosed
US-20240109888-A1 TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2024-04-04 US disclosed
CN-117007691-A Method for detecting content of thermosensitive active protein in liquid milk 上海市质量监督检验技术研究院 2023-11-07 CN disclosed
US-11767322-B2 Triazolopyridinyl compounds as kinase inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2023-09-26 US disclosed
US-20220204636-A1 ANTIBODIES AGAINST HUMAN CD38 GENMAB A/S (DK) 2022-06-30 US disclosed
CN-1859912-A Inhibitors of Akt activity SMITHKLINE BEECHAM CORP (US) 2006-11-08 CN disclosed
WO-2004028452-A2 METHOD FOR PREPARING CRAMBESCIDIN CORE ACID INTERMEDIATES AND THEIR USE FOR PREPARING CRAMBESCIDIN ALKALOID ANALOGS AS THERAPEUTIC AGENTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2004-04-08 WO disclosed
CN-1134539-C Thrombopoietin ��Ĭɭ�����ѧ���޹�˾ 2004-01-14 CN disclosed
US-5643566-A INTERLEUKINS, INTERFERONS, STABILIZERS CETUS CORPORATION (US) 1997-07-01 US disclosed
CN-1141061-A Thrombopoietin GENENTECH INC (US) 1997-01-22 CN disclosed
JP-H03172183-A BRAIN FACTOR EXPRESSION SYSTEM ONCOGEN 1991-07-25 JP disclosed
US-4992271-A Interleukin in aqueous carrier comprising human serum albumin CETUS CORPORATION (US) 1991-02-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220204636-A1 ANTIBODIES AGAINST HUMAN CD38 CD38, CD22, CD2 FAAH 3350/4885CES1 3611/4885CES2 2549/4885
US-20240109888-A1 TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS RIPK1, RIPK3, RIPK4 FAAH 3928/4885CES1 2693/4885CES2 4388/4885
US-11767322-B2 Triazolopyridinyl compounds as kinase inhibitors RIPK1, RIPK3, RIPK4 FAAH 3928/4885CES1 2693/4885CES2 4388/4885
US-12110290-B2 Triazolopyridinyl compounds as kinase inhibitors RIPK1, RIPK3, RIPK4 FAAH 3928/4885CES1 2693/4885CES2 4388/4885
US-20240425505-A1 TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS RIPK1, RIPK3, RIPK4 FAAH 3928/4885CES1 2693/4885CES2 4388/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.