Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 8/20 | 0.45 |
| ▸ | CNR2 | P34972 | 6/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.45 |
| ▸ | CASR | P41180 | 4/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5403135 | 0.75 | MTNR1A (0.46) | MTNR1AMTNR1BCNR1CNR2EPHX2 | |
| SCHEMBL3290730 | 0.71 | HRH1 (0.68) | MTNR1AMTNR1BCASRHTR2AHRH1 | |
| SCHEMBL3674189 | 0.70 | CYP2D6 (0.54) | MTNR1AMTNR1BCNR1CNR2EPHX2 | |
| SCHEMBL7114570 | 0.69 | PTGS2 (0.47) | MTNR1AMTNR1B | |
| SCHEMBL5402685 | 0.69 | TBXAS1 (0.49) | MTNR1AMTNR1BCNR1CNR2EPHX2 | |
| SCHEMBL5410936 | 0.69 | CNR1 (0.50) | MTNR1AMTNR1BCNR1CNR2EPHX2 | |
| SCHEMBL10777977 | 0.69 | HDAC1 (0.41) | HTR2AHRH1 | |
| SCHEMBL2732016 | 0.68 | HRH1 (0.65) | MTNR1AMTNR1BCASRHTR2AHRH1 | |
| SCHEMBL844862 | 0.68 | HRH1 (0.65) | MTNR1AMTNR1BCASRHTR2AHRH1 | |
| SCHEMBL27321444 | 0.68 | HRH1 (0.65) | MTNR1AMTNR1BCASRHTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247645-B2 | Dihydropyridine derivatives | AJINOMOTO CO., INC. (JP) | 2007-07-24 | — | — | US | disclosed |