SCHEMBL540363

SCHEMBL540363

C=C1CCCCC1.N=C=O.N=C=O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
TRIM24 O15164 1/20 0.33
TRIM33 Q9UPN9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL540362 1.00 ALDH1A1 (0.33) ALDH1A1TRIM24TRIM33
SCHEMBL8997440 0.84
SCHEMBL7065109 0.80 TRIM24 (0.38) ALDH1A1TRIM24TRIM33
SCHEMBL1635045 0.80
SCHEMBL7138204 0.80 TRIM24 (0.38) ALDH1A1TRIM24TRIM33
SCHEMBL9292166 0.80
SCHEMBL2221624 0.80 TRIM24 (0.38) ALDH1A1TRIM24TRIM33
SCHEMBL100582 0.80
SCHEMBL104278 0.80
SCHEMBL2221659 0.80 TRIM24 (0.38) ALDH1A1TRIM24TRIM33

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 521 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2720668-A2 COSMETIC USE OF A FLOCCULANT POLYMER AS ANTIPERSPIRANT L'Oréal (FR) 2014-04-23 EP claimed
US-8449871-B2 Composition comprising novel polyurethanes and cosmetic treatment process L'OREAL (FR) 2013-05-28 US claimed
WO-2012175330-A2 COSMETIC USE OF A FLOCCULANT POLYMER AS ANTIPERSPIRANT L'OREAL (FR) 2012-12-27 WO claimed
CN-100588387-C Styling composition comprising, in a predominantly aqueous medium, an elastic cationic polyurethane, processes using it and uses thereof OREAL 2010-02-10 CN claimed
EP-2113243-A1 Cosmetic composition comprising a cationic polyurethane and a cellulose derivative and uses in hairdressing L'Oreal (FR) 2009-11-04 EP claimed
EP-2113244-A1 Cosmetic composition comprising a cationic polyurethane and a specific cationic polymer and uses in hairdressing L'Oréal (FR) 2009-11-04 EP claimed
US-20090130028-A1 Cosmetic composition comprising a cationic polyurethane and a silicone, to be applied during hair dressing L'OREAL S.A. (FR) 2009-05-21 US claimed
CN-101259090-A Cosmetic composition comprising a cationic polyurethane and a silicone and application to hairdressing OREAL (FR) 2008-09-10 CN claimed
US-20080206177-A1 Cosmetic composition comprising at least one cationic polyurethane and at least one polyethylene glycol ester, to be applied during hair dressing L'OREAL, S.A. (FR) 2008-08-28 US claimed
US-20080206164-A1 Cosmetic composition comprising at least one cationic polyurethane and at least one vinyl pyrrolidone homo- or copolymer, and method of styling therewith L'OREAL S.A. (FR) 2008-08-28 US claimed
US-20070283977-A1 Composition comprising novel polyurethanes and cosmetic treatment process L'OREAL S.A. (FR) 2007-12-13 US claimed
EP-1837353-A1 New polyurethanes, ingredients which include them and cosmetic treatment method L'OREAL (FR) 2007-09-26 EP claimed
EP-1645579-A1 Cationic or cationisable elastic polyurethane L'OREAL (FR) 2006-04-12 EP claimed
US-20060067907-A1 Cationic or cationizable polyurethane with elastic character L'OREAL S.A. (FR) 2006-03-30 US claimed
CN-1650840-A Styling composition comprising, in a predominantly aqueous medium, an elastic cationic polyurethane, processes using it and uses thereof OREAL (FR) 2005-08-10 CN claimed
US-20050169873-A1 Styling composition comprising, in a predominantly aqueous medium, an elastic cationic polyurethane, processes using it and uses thereof L'OREAL S.A. (FR) 2005-08-04 US claimed
US-20040197293-A1 Anionic polyurethanes with elastic property L'OREAL S.A. (FR) 2004-10-07 US claimed
US-20040052753-A1 Cationic polyurethanes with elastic character L'OREAL (FR) 2004-03-18 US claimed
US-20040001798-A1 Self-adhesive cationic or amphoteric polyurethanes L'OREAL (FR) 2004-01-01 US claimed
EP-1323756-A1 Cationic or amphoteric polyurethane adhesives L'OREAL (FR) 2003-07-02 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060067907-A1 Cationic or cationizable polyurethane with elastic character PUF60, H1-2, H1-0 ALDH1A1 3346/4885TRIM24 1806/4885TRIM33 4350/4885
US-20040052753-A1 Cationic polyurethanes with elastic character PUF60, H1-0, HNRNPA3 ALDH1A1 1555/4885TRIM24 2077/4885TRIM33 3259/4885
US-20080206164-A1 Cosmetic composition comprising at least one cationic polyurethane and at least one vinyl pyrrolidone homo- or copolymer, and method of styling therewith PUF60, SRSF2, PCBP1 ALDH1A1 2636/4885TRIM24 2617/4885TRIM33 1301/4885
US-20090130028-A1 Cosmetic composition comprising a cationic polyurethane and a silicone, to be applied during hair dressing CUTA, NONO, DPM1 ALDH1A1 3282/4885TRIM24 3297/4885TRIM33 1484/4885
US-20050169873-A1 Styling composition comprising, in a predominantly aqueous medium, an elastic cationic polyurethane, processes using it and uses thereof POLR1C, NACA, PIK3C3 ALDH1A1 4697/4885TRIM24 2602/4885TRIM33 1823/4885
US-20070283977-A1 Composition comprising novel polyurethanes and cosmetic treatment process UROD, PUF60, CUTA ALDH1A1 994/4885TRIM24 4364/4885TRIM33 4172/4885
US-20080206177-A1 Cosmetic composition comprising at least one cationic polyurethane and at least one polyethylene glycol ester, to be applied during hair dressing CUTA, PHOSPHO1, DSG1 ALDH1A1 1285/4885TRIM24 2928/4885TRIM33 2694/4885
US-20040197293-A1 Anionic polyurethanes with elastic property PUF60, PHOSPHO1, PLA2G2C ALDH1A1 1763/4885TRIM24 3466/4885TRIM33 4770/4885
US-20040001798-A1 Self-adhesive cationic or amphoteric polyurethanes PARN, PCNA, FSCN1 ALDH1A1 3074/4885TRIM24 1126/4885TRIM33 910/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.