Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | FURIN | P09958 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1493053 | 0.84 | CYP3A4 (0.52) | ALDH1A1L3MBTL1CYP3A4TSHRFURIN | |
| SCHEMBL10341873 | 0.84 | CYP3A4 (0.52) | L3MBTL1CYP3A4TSHRFURINCYP1A2 | |
| SCHEMBL27683603 | 0.84 | CYP3A4 (0.42) | ALDH1A1L3MBTL1CYP3A4TSHRFURIN | |
| SCHEMBL7602206 | 0.83 | TSHR (0.50) | L3MBTL1CYP3A4TSHRFURINHDAC1 | |
| SCHEMBL10703892 | 0.83 | TSHR (0.50) | L3MBTL1CYP3A4TSHRFURINHDAC1 | |
| SCHEMBL10341829 | 0.82 | CYP3A4 (0.54) | ALDH1A1L3MBTL1CYP3A4TSHRFURIN | |
| SCHEMBL3070544 | 0.81 | CYP3A4 (0.50) | ALDH1A1L3MBTL1CYP3A4TSHRFURIN | |
| SCHEMBL2454654 | 0.81 | CA12 (0.49) | ALDH1A1CYP3A4TSHRHPGDLMNA | |
| SCHEMBL414168 | 0.80 | CYP1A2 (0.50) | CYP3A4TSHRCYP1A2CYP2C9CYP19A1 | |
| SCHEMBL7898652 | 0.78 | TSHR (0.46) | L3MBTL1CYP3A4TSHRFURINGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342592-B1 | FUNCTIONALIZED ALKENOXYARYL OR ALKENYLARYLOXYARYL COMPOUND; SEPARATING ENANTIOMORPHS USING THREE-DIMENSIONAL NETWORKS; CHROMATOGRAPHY | INSTITUT FRANCAIS DU PETROLE AND CHIRALSEP (FR) | 2002-01-29 | — | — | US | claimed |
| US-7230123-B2 | Ureido or carbamate derivatives of crown ethers and of silicon usable for preparing supports intended for the separation by chromatography of metal cations and of organic molecules comprising amine functional groups | COMMISSARIAT A L'ENERGIR ATOMIQUE (FR) | 2007-06-12 | — | — | US | disclosed |
| US-7230123-B2 | Ureido or carbamate derivatives of crown ethers and of silicon usable for preparing supports intended for the separation by chromatography of metal cations and of organic molecules comprising amine functional groups | COMMISSARIAT A L'ENERGIR ATOMIQUE (FR) | 2007-06-12 | — | — | US | disclosed |
| EP-1483272-B1 | UREA OR CARBAMATE DERIVATIVES OF CROWN ETHERS AND SILICON USEFUL FOR THE PREPARATION OF SUPPORTS FOR CHROMATOGRAPHIC SEPARATION OF METAL CATIONS AND ORGANIC MOLECULES COMPRISING AN AMINO FUNCTION | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2006-01-11 | — | — | EP | disclosed |
| US-20050143587-A1 | Ureido or carbamate derivatives of crown ethers and of silicon usable for preparing supports intended for the separation by chromatography of metal cations and of organic molecules comprising amine functional groups | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2005-06-30 | — | — | US | disclosed |
| EP-1483272-A1 | UREA OR CARBAMATE DERIVATIVES OF CROWN ETHERS AND SILICON USEFUL FOR THE PREPARATION OF SUPPORTS FOR CHROMATOGRAPHIC SEPARATION OF METAL CATIONS AND ORGANIC MOLECULES COMPRISING AN AMINO FUNCTION | Commissariat à l'Energie Atomique (FR) | 2004-12-08 | — | — | EP | disclosed |
| WO-2003062250-A1 | UREA OR CARBAMATE DERIVATIVES OF CROWN ETHERS AND SILICON USEFUL FOR THE PREPARATION OF SUPPORTS FOR CHROMATOGRAPHIC SEPARATION OF METAL CATIONS AND ORGANIC MOLECULES COMPRISING AN AMINO FUNCTION | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2003-07-31 | — | — | WO | disclosed |
| EP-0864586-B1 | Chiral supports and use thereof in the preparation or separation of enantiomers | INST FRANCAIS DU PETROLE (FR) | 2002-04-03 | — | — | EP | disclosed |
| US-6342592-B1 | FUNCTIONALIZED ALKENOXYARYL OR ALKENYLARYLOXYARYL COMPOUND; SEPARATING ENANTIOMORPHS USING THREE-DIMENSIONAL NETWORKS; CHROMATOGRAPHY | INSTITUT FRANCAIS DU PETROLE AND CHIRALSEP (FR) | 2002-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143587-A1 | Ureido or carbamate derivatives of crown ethers and of silicon usable for preparing supports intended for the separation by chromatography of metal cations and of organic molecules comprising amine functional groups | UTS2R, SRM, SMOX | ALDH1A1 3701/4885L3MBTL1 4661/4885CYP3A4 1272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.